Computational repurposing of drugs for viral diseases and current and future pandemics
DA Winkler - Journal of Mathematical Chemistry, 2024 - Springer
A large fraction of the world's population is directly impacted by acute or chronic viral
infections, many of which have high mortality. As was brought home to us in 2020, viruses …
infections, many of which have high mortality. As was brought home to us in 2020, viruses …
Artificial Intelligence, machine learning, and big data for Ebola virus drug discovery
The effect of Ebola virus disease (EVD) is fatal and devastating, necessitating several efforts
to identify potent biotherapeutic molecules. This review seeks to provide perspectives on …
to identify potent biotherapeutic molecules. This review seeks to provide perspectives on …
Open MoA: revealing the mechanism of action (MoA) based on network topology and hierarchy
Motivation Many approaches in systems biology have been applied in drug repositioning
due to the increased availability of the omics data and computational biology tools. Using a …
due to the increased availability of the omics data and computational biology tools. Using a …
EBOLApred: A machine learning-based web application for predicting cell entry inhibitors of the Ebola virus
J Adams, K Agyenkwa-Mawuli, O Agyapong… - … Biology and Chemistry, 2022 - Elsevier
Ebola virus disease (EVD) is a highly virulent and often lethal illness that affects humans
through contact with the body fluid of infected persons. Glycoprotein and matrix protein VP40 …
through contact with the body fluid of infected persons. Glycoprotein and matrix protein VP40 …
Databases, Knowledgebases, and Software Tools for Virus Informatics
Y Lin, Y Qian, X Qi, B Shen - … Informatics: Prevention and Treatment of Viral …, 2022 - Springer
Virus infection is a common social health issue. In the past decades, serious virus infectious
events have caused great loss in people's life and the economics. The nature of rapid …
events have caused great loss in people's life and the economics. The nature of rapid …