▪ Abstract Modern chemotherapy has played a major role in our control of tuberculosis. Yet
tuberculosis still remains a leading infectious disease worldwide, largely owing to …

Tuberculosis (TB) claims a life every 10 seconds and global mortality rates are increasing
despite the use of chemotherapy. But why have we not progressed towards the eradication …

BACKGROUND: Delamanid (OPC-67683) is a novel mycolic acid biosynthesis inhibitor
active against Mycobacterium tuberculosis at a low minimum inhibitory concentration …

OBJECTIVE: To evaluate the early bactericidal activity (EBA) of the new fluoroquinolones
levofloxacin, gatifloxacin and moxifloxacin in patients with pulmonary tuberculosis (PTB) …

With nearly one-third of the global population infected by Mycobacterium tuberculosis, TB
remains a major cause of death (1.7 million in 2006). TB is particularly severe in parts of …

Despite advances in chemotherapy and the BCG (Bacillus Calmette–Guérin) vaccine,
tuberculosis remains a significant infectious disease. Although it can be cured, the therapy …

Over three previous editions, Clinical Tuberculosis has established itself as an
indispensable guide to all aspects of tuberculosis diagnosis and treatment. This fully revised …

We examined sputum bacterial loads in adults with newly diagnosed tuberculosis using
quantitative culture and time-until-positive (DTP) culture in BACTEC 460. Patients with …

Quantification of mycobacteria in sputum from pulmonary tuberculosis patients has been
used to evaluate patient's response to treatment since the earliest days of anti-tuberculosis …

This completely revised and expanded Second Edition thoroughly examines tuberculosis
from historical, theoretical, and clinical perspectives, including the most current discoveries …