Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

Publisher Summary This chapter summarizes recent information on the function of high-
mobility-group (HMG) proteins. Advances in this field were made primarily by elucidating the …

The AT-hook is a small DNA-binding protein motif which was first described in the high
mobility group non-histone chromosomal protein HMG-I (Y). Since its discovery, this motif …

Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

Members of the HMGA (aka HMGI/Y) family of 'high mobility group'(HMG) proteins
participate in a wide variety of nuclear processes ranging from chromosome and chromatin …

We recently showed that the 1.7 megabase multiple aberration region (MAR) on human
chromosome 12q15 harbours recurrent breakpoints frequently found in a variety of benign …

The mammalian HMGI/Y (HMGA) non-histone proteins participate in a wide variety of
cellular processes including regulation of inducible gene transcription, integration of …

Although the three families of mammalian HMG proteins (HMGA, HMGB and HMGN)
participate in many of the same nuclear processes, each family plays its own unique role in …

The 'high mobility group'HMGA protein family consists of four members: HMGA1a, HMGA1b
and HMGA1c, which result from translation of alternative spliced forms of one gene and …

The HMGI protein family includes three proteins, named HMG-I, HMG-Y and HMGI-C. The
first two proteins are coded for by the same gene, HMGI (Y), through an alternative splicing …