Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3′-sialyllactose and 6′-sialyllactose
Y Zhu, J Zhang, W Zhang, W Mu - Biotechnology Advances, 2023 - Elsevier
Human milk oligosaccharides (HMOs), the third major solid component in breast milk, are
recognized as the first prebiotics for health benefits in infants. Sialylated HMOs are an …
recognized as the first prebiotics for health benefits in infants. Sialylated HMOs are an …
Functional effects of human milk oligosaccharides (HMOs)
Human milk oligosaccharides (HMOs) are the third most important solid component in
human milk and act in tandem with other bioactive components. Individual HMO levels and …
human milk and act in tandem with other bioactive components. Individual HMO levels and …
Biology of human milk oligosaccharides: From basic science to clinical evidence
Human milk oligosaccharides (HMOs) have been researched by scientists for over 100
years, driven by the substantial evidence for the nutritional and health benefits of mother's …
years, driven by the substantial evidence for the nutritional and health benefits of mother's …
Human milk: From complex tailored nutrition to bioactive impact on child cognition and behavior
Human milk is a highly complex liquid food tailor-made to match an infant's needs. Beyond
documented positive effects of breastfeeding on infant and maternal health, there is …
documented positive effects of breastfeeding on infant and maternal health, there is …
Sialic acid, the secret gift for the brain
F Liu, AB Simpson, E D'Costa, FS Bunn… - Critical Reviews in …, 2023 - Taylor & Francis
The human brain grows rapidly in early life which requires adequate nutrition. Human milk
provides optimal nutrition for the developing brain, and breastfeeding significantly improves …
provides optimal nutrition for the developing brain, and breastfeeding significantly improves …
An extensively hydrolyzed formula supplemented with two human milk oligosaccharides modifies the fecal microbiome and metabolome in infants with cow's milk …
CL Boulangé, HK Pedersen, FP Martin… - International Journal of …, 2023 - mdpi.com
Cow's milk protein allergy (CMPA) is a prevalent food allergy among infants and young
children. We conducted a randomized, multicenter intervention study involving 194 non …
children. We conducted a randomized, multicenter intervention study involving 194 non …
Effects of an extensively hydrolyzed formula supplemented with two human milk oligosaccharides on growth, tolerability, safety and infection risk in infants with cow's …
Y Vandenplas, M Żołnowska, R Berni Canani… - Nutrients, 2022 - mdpi.com
This randomized clinical trial (Registration: NCT03085134) assessed if an extensively
hydrolyzed formula (EHF) supplemented with two human milk oligosaccharides (HMO) and …
hydrolyzed formula (EHF) supplemented with two human milk oligosaccharides (HMO) and …
CRISPR-Cas-based identification of a sialylated human milk oligosaccharides utilization cluster in the infant gut commensal Bacteroides dorei
S Kijner, D Ennis, S Shmorak, A Florentin… - Nature …, 2024 - nature.com
The infant gut microbiome is impacted by early-life feeding, as human milk oligosaccharides
(HMOs) found in breastmilk cannot be digested by infants and serve as nutrients for their gut …
(HMOs) found in breastmilk cannot be digested by infants and serve as nutrients for their gut …
Infant formula with a specific blend of five human milk oligosaccharides drives the gut microbiota development and improves gut maturation markers: A randomized …
M Bosheva, I Tokodi, A Krasnow, HK Pedersen… - Frontiers in …, 2022 - frontiersin.org
Background Human milk oligosaccharides (HMOs) have important biological functions for a
healthy development in early life. Objective This study aimed to investigate gut maturation …
healthy development in early life. Objective This study aimed to investigate gut maturation …