Semantic similarity and machine learning with ontologies
Ontologies have long been employed in the life sciences to formally represent and reason
over domain knowledge and they are employed in almost every major biological database …
over domain knowledge and they are employed in almost every major biological database …
The human phenotype ontology in 2017
Deep phenotyping has been defined as the precise and comprehensive analysis of
phenotypic abnormalities in which the individual components of the phenotype are observed …
phenotypic abnormalities in which the individual components of the phenotype are observed …
The comparative toxicogenomics database: update 2019
AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is a premier
public resource for literature-based, manually curated associations between chemicals …
public resource for literature-based, manually curated associations between chemicals …
Genomics and taxonomy in diagnostics for food security: soft-rotting enterobacterial plant pathogens
L Pritchard, RH Glover, S Humphris… - Analytical …, 2016 - pubs.rsc.org
Soft rot Enterobacteriaceae (SRE) are bacterial plant pathogens that cause blackleg, wilt
and soft rot diseases on a broad range of important crop and ornamental plants worldwide …
and soft rot diseases on a broad range of important crop and ornamental plants worldwide …
[HTML][HTML] The genetic basis of Mendelian phenotypes: discoveries, challenges, and opportunities
JX Chong, KJ Buckingham, SN Jhangiani… - The American Journal of …, 2015 - cell.com
Discovering the genetic basis of a Mendelian phenotype establishes a causal link between
genotype and phenotype, making possible carrier and population screening and direct …
genotype and phenotype, making possible carrier and population screening and direct …
[图书][B] Plant functional diversity: organism traits, community structure, and ecosystem properties
Biological diversity, the variety of living organisms on Earth, is traditionally viewed as the
diversity of taxa, and species in particular. However, other facets of diversity also need to be …
diversity of taxa, and species in particular. However, other facets of diversity also need to be …
[PDF][PDF] The human phenotype ontology in 2017
Deep phenotyping has been defined as the precise and comprehensive analysis of
phenotypic abnormalities in which the individual components of the phenotype are observed …
phenotypic abnormalities in which the individual components of the phenotype are observed …
Open Science principles for accelerating trait-based science across the Tree of Life
Synthesizing trait observations and knowledge across the Tree of Life remains a grand
challenge for biodiversity science. Species traits are widely used in ecological and …
challenge for biodiversity science. Species traits are widely used in ecological and …
[HTML][HTML] Systematic phenomics analysis deconvolutes genes mutated in intellectual disability into biologically coherent modules
K Kochinke, C Zweier, B Nijhof, M Fenckova… - The American Journal of …, 2016 - cell.com
Intellectual disability (ID) disorders are genetically and phenotypically extremely
heterogeneous. Can this complexity be depicted in a comprehensive way as a means of …
heterogeneous. Can this complexity be depicted in a comprehensive way as a means of …
Seven shortfalls that beset large-scale knowledge of biodiversity
J Hortal, F de Bello, JAF Diniz-Filho… - Annual review of …, 2015 - annualreviews.org
Ecologists and evolutionary biologists are increasingly using big-data approaches to tackle
questions at large spatial, taxonomic, and temporal scales. However, despite recent efforts …
questions at large spatial, taxonomic, and temporal scales. However, despite recent efforts …