RNAi-mediated inhibition of SARS-CoV-2: applications and challenges
D Sanyal, B Chaubey - Future Virology, 2024 - Taylor & Francis
The global pandemic due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), has led to∼ 6.9 million deaths and affected∼ 767 million people globally. The approved …
2), has led to∼ 6.9 million deaths and affected∼ 767 million people globally. The approved …
[HTML][HTML] In silico prediction and experimental validation of siRNAs targeting ORF1ab of MERS-CoV in Vero cell line
Abstract The Middle East Respiratory Syndrome Coronavirus is well known to cause
respiratory syndrome and this virus was identified and isolated for the first time from Jeddah …
respiratory syndrome and this virus was identified and isolated for the first time from Jeddah …
Anti‐HCV Activity from Semi‐purified Methanolic Root Extracts of Valeriana wallichii
KK Ganta, A Mandal, S Debnath, B Hazra… - Phytotherapy …, 2017 - Wiley Online Library
Hepatitis C virus (HCV) is a serious global health problem affecting approximately 130–150
million individuals. Presently available direct‐acting anti‐HCV drugs have higher barriers to …
million individuals. Presently available direct‐acting anti‐HCV drugs have higher barriers to …
Multiple gene targeting siRNAs for down regulation of Immediate Early-2 (Ie2) and DNA polymerase genes mediated inhibition of novel rat Cytomegalovirus (strain All …
Background Cytomegalovirus (CMV) is an opportunistic pathogen that causes severe
complications in congenitally infected newborns and non-immunocompetent individuals …
complications in congenitally infected newborns and non-immunocompetent individuals …
Generation of combinatorial lentiviral vectors expressing multiple anti-hepatitis C virus shRNAs and their validation on a novel HCV replicon double reporter cell line
HM Elbadawy, MI Mohammed Abdul, N Aljuhani… - Viruses, 2020 - mdpi.com
Despite the introduction of directly acting antivirals (DAAs), for the treatment of hepatitis C
virus (HCV) infection, their cost, patient compliance, and viral resistance are still important …
virus (HCV) infection, their cost, patient compliance, and viral resistance are still important …
Is the conquest of Hepatitis C imminent?
L Rivett, G Alexander - Expert reviews in molecular medicine, 2019 - cambridge.org
Hepatitis C virus represents a global pathogen of human health significance. In the space of
less than three decades, we have witnessed the discovery of the virus, a growing …
less than three decades, we have witnessed the discovery of the virus, a growing …
[PDF][PDF] Effect of RNA interference on the hepatitis C virus core expression in HepG2/C3A cells using genotype 4 isolates from Saudi patients
MK Shier, HH Ali, MS El-Wetidy… - J Coll Physicians …, 2019 - academia.edu
Objective: To explore the effects of two different methodologies of RNA interference, namely
small interfering RNA, and vector-based short hairpin RNA, on the expression levels of …
small interfering RNA, and vector-based short hairpin RNA, on the expression levels of …
Expression of duplex shRNAs through a lentiviral vector against cellular and viral genes inflicts sustained inhibition of hepatitis C virus replication
A Mandal, B Chaubey - Intervirology, 2018 - karger.com
Background: The RNAi-based transient therapeutic approach has been well explored for its
potential against the hepatitis V virus (HCV). However, to achieve a sustained virological …
potential against the hepatitis V virus (HCV). However, to achieve a sustained virological …
In silico Prediction and Cytotoxicity Evaluation of siRNAs Targeting Conserved Regions of MERS-CoV in Cell Culture
Abstract The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was isolated in
2012 and is well known to cause the respiratory syndrome. The orf1ab gene is known to …
2012 and is well known to cause the respiratory syndrome. The orf1ab gene is known to …
[PDF][PDF] Сравнительное изучение некоторых биохимических показателей и цитокинов при вирусном гепатите С
ЛР ТАЛЫШИНСКАЯ - health-medix.com
Резюме Целью данной работы было исследование диагностического и
прогностического значений биохимических показателей крови и уровня некоторых …
прогностического значений биохимических показателей крови и уровня некоторых …