Brief introduction of current technologies in isolation of broadly neutralizing HIV-1 antibodies
HIV/AIDS has become a worldwide pandemic. Before an effective HIV-1 vaccine eliciting
broadly neutralizing monoclonal antibodies (bnmAbs) is fully developed, passive …
broadly neutralizing monoclonal antibodies (bnmAbs) is fully developed, passive …
DNA prime/MVTT boost regimen with HIV-1 mosaic Gag enhances the potency of antigen-specific immune responses
W Liu, YC Wong, SMY Chen, J Tang, H Wang… - Vaccine, 2018 - Elsevier
HIV-1 diversity and latent reservoir are the major challenges for the development of an
effective AIDS vaccine. It is well indicated that Gag-specific CD8+ T cells serve as the …
effective AIDS vaccine. It is well indicated that Gag-specific CD8+ T cells serve as the …
Vaccine based on antibody-dependent cell-mediated cytotoxicity epitope on the H1N1 influenza virus increases mortality in vaccinated mice
J Wang, M Liu, N Ding, Y Li, J Shao, M Zhu… - Biochemical and …, 2018 - Elsevier
Antibody-dependent cell-mediated cytotoxicity bridges humoral immunity and cellular
immunity. Thus vaccine candidates which can elicit both broadly neutralizing antibodies and …
immunity. Thus vaccine candidates which can elicit both broadly neutralizing antibodies and …
Identification of a HIV gp41-specific human monoclonal antibody with potent antibody-dependent cellular cytotoxicity
Z Yang, X Liu, Z Sun, J Li, W Tan, W Yu… - Frontiers in …, 2018 - frontiersin.org
Antibody-Dependent Cellular Cytotoxicity (ADCC) is a major mechanism of protection
against viral infections in vivo. Identification of HIV-1-specific monoclonal antibodies (mAbs) …
against viral infections in vivo. Identification of HIV-1-specific monoclonal antibodies (mAbs) …
[PDF][PDF] Generation of immortalized human naïve B cell libraries by optimized EBV transformation
S Lu, Z Sun, M Zhang - Journal of Medical Discovery, 2016 - e-discoverypublication.com
Epstein–Barr virus (EBV) transformation is a useful tool in generating immortalized B cells.
However, the B cell immortalization efficiency is quite low in conventional method of EBV …
However, the B cell immortalization efficiency is quite low in conventional method of EBV …
Construction of a recombinant full-length membrane associated IgG library
Z Sun, S Lu, Z Yang, J Li, M Zhang - Virus Research, 2017 - Elsevier
HIV/AIDS has become a global pandemic. Development of an effective HIV-1 vaccine
eliciting broadly neutralizing monoclonal antibodies (bnmAbs) remains a big challenge …
eliciting broadly neutralizing monoclonal antibodies (bnmAbs) remains a big challenge …
[HTML][HTML] 人B 细胞永生化研究进展
钟周玥， 于思远， 葛胜祥 - 生物工程学报, 2021 - cjb.ijournals.cn
人源单克隆抗体具有免疫原性低, 半衰期长等优势, 成为了体内应用中不可或缺的生物制剂.
人类抗体库为人源单克隆抗体的制备提供了丰富的来源, 人B 细胞永生化是获得人类抗体库的 …
人类抗体库为人源单克隆抗体的制备提供了丰富的来源, 人B 细胞永生化是获得人类抗体库的 …
[PDF][PDF] Broadly Neutralizing Antibodies (BNAbs): templates for HIV-1 vaccine design
L Yan, R Zhang, L Liu, Y Wang… - Journal of Medical …, 2017 - e-discoverypublication.com
1Harbin Medical University Affiliated 2nd Hospital, 246 Xuefu Road, Harbin, China, 150086.
2The Aaron Diamond AIDS Research Center. 455 First Avenue, New York, NY, 10016, USA …
2The Aaron Diamond AIDS Research Center. 455 First Avenue, New York, NY, 10016, USA …
[HTML][HTML] Journal of Veterinary Medicine and Animal Sciences
Z Sun - meddocsonline.org
Passive immunization for prevention and treatment of HIV-1 infection still plays important
roles in fighting against HIV/AIDS. Recently, a panel of potent broadly neutralizing …
roles in fighting against HIV/AIDS. Recently, a panel of potent broadly neutralizing …
Characterization of a monoclonal antibody that binds to both gp120 and gp41
H Zheng, J Tang, S Lu, Q Qian, W Liu, Z Yang… - Future …, 2018 - Taylor & Francis
Aim: AIDS has become a global pandemic. Characterization of broadly HIV-1-neutralizing
antibodies (bnAbs) may facilitate the vaccine design. Methods & materials: Recombinant …
antibodies (bnAbs) may facilitate the vaccine design. Methods & materials: Recombinant …