DNA encodes the genetic information; recently, it has also become a key player in material
science. Given the specific Watson–Crick base‐pairing interactions between only four types …

Over the last decade, the number of cancer survivors has increased thanks to progress in
diagnosis and treatment. Cancer treatments are often accompanied by adverse side effects …

Membrane trafficking pathways emanating from the Golgi regulate a wide range of cellular
processes. One of these is the maintenance of copper (Cu) homeostasis operated by the …

Resistance to platinum-based chemotherapy is a major clinical challenge in ovarian cancer,
contributing to the high mortality-to-incidence ratio. Management of the platinum-resistant …

In the search of new alternative anticancer agents, essential oils (Eos) play a critical role,
exerting selective anti-cancer properties and limiting the toxicity of conventional therapies …

DNA repair defects are important factors in cancer development. High DNA repair activity
can affect cancer progression and chemoresistance. DNA double-strand breaks in cancer …

Endogenous electrophiles, ionizing and non-ionizing radiation, and hazardous chemicals
present in the environment and diet can damage DNA by forming covalent adducts. DNA …

Skin cancer is one of the cancers that registers the highest number of new cases annually.
Among all forms of skin cancer, melanoma is the most invasive and deadliest. The …

Many chemotherapeutic drugs exert their cytotoxicity through the formation of DNA
modifications (adducts), which interfere with DNA replication, an overactive process in …

DNA adducting drugs, including alkylating agents and platinum-containing drugs, are
prominent in cancer chemotherapy. Their mechanisms of action involve direct interaction …