Epigenetic regulation in oral squamous cell carcinoma microenvironment: a comprehensive review

H Mesgari, S Esmaelian, K Nasiri, S Ghasemzadeh… - Cancers, 2023 - mdpi.com
Simple Summary This comprehensive review focuses on the role of epigenetics in oral
squamous cell carcinoma (OSCC), a prevalent type of oral cancer. The review highlights the …

Head and neck cancers are not alike when tarred with the same brush: An epigenetic perspective from the cancerization field to prognosis

D Camuzi, TA Simão, F Dias, LF Ribeiro Pinto… - Cancers, 2021 - mdpi.com
Simple Summary Squamous cell carcinomas affect different head and neck subsites and,
although these tumors arise from the same epithelial lining and share risk factors, they differ …

Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers

M Inchanalkar, S Srivatsa, S Ambatipudi, PG Bhosale… - Clinical …, 2023 - Springer
Background Gingivobuccal complex oral squamous cell carcinoma (GBC-OSCC) is an
aggressive malignancy with high mortality often preceded by premalignant lesions …

Hypermethylation-mediated lncRNA MAGI2-AS3 downregulation facilitates malignant progression of laryngeal squamous cell carcinoma via interacting with SPT6

J Wang, C Yang, H Cao, J Yang, W Meng… - Cell …, 2023 - journals.sagepub.com
Long noncoding RNAs (lncRNAs) have an effect on the occurrence and progression of a
considerable number of diseases, especially cancer. Existing research has suggested that …

Oral tumor heterogeneity, its implications for patient monitoring and designing anti-cancer strategies

R Mishra - Pathology-Research and Practice, 2023 - Elsevier
Oral cancer tumors occur in the mouth and are mainly derived from oral mucosa linings. It is
one of the most common and fatal malignant diseases worldwide. The intratumor …

[HTML][HTML] Universal penalized regression (Elastic-net) model with differentially methylated promoters for oral cancer prediction

S Das, S Karuri, J Chakraborty… - European …, 2024 - eurjmedres.biomedcentral.com
DNA methylation showed notable potential to act as a diagnostic marker in many cancers.
Many studies proposed DNA methylation biomarker in OSCC detection, while most of these …

FBXL7 Body Hypomethylation Is Frequent in Tumors from the Digestive and Respiratory Tracts and Is Associated with Risk-Factor Exposure

D Camuzi, LA Buexm, SQC Lourenço… - International Journal of …, 2022 - mdpi.com
Squamous cell carcinoma is the main histological tumor type in the upper aerodigestive tract
(UADT), including the esophagus (ESCC) and the head and neck sites, as well as the oral …

MYEOV with High Frequencies of Mutations in Head and Neck Cancers Facilitates Cancer Cell Malignant Behaviors

D Ou, Y Wu, J Zhang, J Liu, Z Liu, M Shao, X Guo… - Biochemical …, 2024 - Springer
Cancer driver genes (CDGs) and the driver mutations disrupt the homeostasis of numerous
critical cell activities, thereby playing a critical role in tumor initiation and progression. In this …

Assessing the Differential Methylation Analysis Quality for Microarray and NGS Platforms

A Budkina, YA Medvedeva, A Stupnikov - International Journal of …, 2023 - mdpi.com
Differential methylation (DM) is actively recruited in different types of fundamental and
translational studies. Currently, microarray-and NGS-based approaches for methylation …