Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

Clinical application of growth factors and cytokines in wound healing

S Barrientos, H Brem, O Stojadinovic… - Wound repair and …, 2014 - Wiley Online Library
Wound healing is a complex and dynamic biological process that involves the coordinated
efforts of multiple cell types and is executed and regulated by numerous growth factors and …

Growth factors and cytokines in wound healing

S Barrientos, O Stojadinovic, MS Golinko… - Wound repair and …, 2008 - Wiley Online Library
Wound healing is an evolutionarily conserved, complex, multicellular process that, in skin,
aims at barrier restoration. This process involves the coordinated efforts of several cell types …

[HTML][HTML] Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

SE Maynard, JY Min, J Merchan… - The Journal of …, 2003 - Am Soc Clin Investig
Preeclampsia, a syndrome affecting 5% of pregnancies, causes substantial maternal and
fetal morbidity and mortality. The pathophysiology of preeclampsia remains largely …

Vascular endothelial growth factor: basic science and clinical progress

N Ferrara - Endocrine reviews, 2004 - academic.oup.com
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and
an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major …

The role of vascular endothelial growth factor in wound healing

P Bao, A Kodra, M Tomic-Canic, MS Golinko… - Journal of Surgical …, 2009 - Elsevier
BACKGROUND: A chronic wound is tissue with an impaired ability to heal. This is often a
consequence of one of the following etiologies: diabetes, venous reflux, arterial insufficiency …

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF …

YJ Surh, KS Chun, HH Cha, SS Han, YS Keum… - Mutation Research …, 2001 - Elsevier
A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death‐dependent pulmonary endothelial cell proliferation and severe pulmonary …

L TARASEVICIENE‐STEWART, Y Kasahara… - The FASEB …, 2001 - Wiley Online Library
Our understanding of the pathobiology of severe pulmonary hypertension, usually a fatal
disease, has been hampered by the lack of information of its natural history. We have …

Molecular and biological properties of vascular endothelial growth factor

N Ferrara - Journal of molecular medicine, 1999 - Springer
Vascular endothelial growth factor (VEGF) is a fundamental regulator of normal and
abnormal angiogenesis. Recent evidence indicates that VEGF is essential for embryonic …

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.

A Papapetropoulos, G García-Cardeña… - The Journal of …, 1997 - Am Soc Clin Investig
Vascular endothelial growth factor (VEGF) is a regulator of vasculogenesis and
angiogenesis. To investigate the role of nitric oxide (NO) in VEGF-induced proliferation and …