New insights in RBM20 cardiomyopathy

D Lennermann, J Backs… - Current heart failure …, 2020 - Springer
Abstract Purpose of Review This review aims to give an update on recent findings related to
the cardiac splicing factor RNA-binding motif protein 20 (RBM20) and RBM20 …

Molecular mechanisms of emerging therapeutic targets in Alzheimer's disease: a systematic review

T Premkumar, S Sajitha Lulu - Neurochemical Journal, 2022 - Springer
Alzheimer's disease (AD) is a severe cognitive impairment considered to be the leading
cause of dementia worldwide. The pathophysiology includes extracellular accumulation of …

DNA methylation profiles in a group of workers occupationally exposed to nanoparticles

A Rossnerova, K Honkova, D Pelclova… - International Journal of …, 2020 - mdpi.com
The risk of exposure to nanoparticles (NPs) has rapidly increased during the last decade
due to the vast use of nanomaterials (NMs) in many areas of human life. Despite this fact …

Conserved immunomodulatory transcriptional networks underlie antipsychotic-induced weight gain

RC Zapata, BS Chaudry, ML Valencia, D Zhang… - Translational …, 2021 - nature.com
Although antipsychotics, such as olanzapine, are effective in the management of psychiatric
conditions, some patients experience excessive antipsychotic-induced weight gain (AIWG) …

[HTML][HTML] Diet-Induced Obesity Induces Transcriptomic Changes in Neuroimmunometabolic-Related Genes in the Striatum and Olfactory Bulb

RB Jaime-Lara, C Colina-Prisco… - International Journal of …, 2024 - mdpi.com
The incidence of obesity has markedly increased globally over the last several decades and
is believed to be associated with the easier availability of energy-dense foods, including …

LipGene: Lipschitz continuity guided adaptive learning rates for fast convergence on microarray expression data sets

T Prashanth, S Saha, S Basarkod… - … ACM transactions on …, 2021 - ieeexplore.ieee.org
Hyperparameter tuning, specifically tuning of learning rate, can often be a time-consuming
process, especially when dealing with large data sets. A mathematical foundation in the …

The state of data science in genomic nursing

C Dreisbach, TA Koleck - Biological Research for Nursing, 2020 - journals.sagepub.com
Nurse scientists are generating, acquiring, distributing, processing, storing, and analyzing
greater volumes of complex omics data than ever before. To take full advantage of big omics …

The Therapeutic Effectiveness of Laparoscopic Sleeve Gastrectomy Among Individuals with Low BMI Obesity (30-35 Kg/m2) and the Relationship of BMI to Weight …

Z Yue, Y Jin, H Sha, Q Wu, L Li, Y Xia… - International Journal of …, 2024 - Taylor & Francis
Purpose Investigating the therapeutic efficacy of Laparoscopic Sleeve Gastrectomy (LSG) in
low BMI (30–35 kg/m2) patients with obesity, and exploring the correlation between patients' …

Gene co-expression networks are associated with obesity-related traits in kidney transplant recipients

RB Jaime-Lara, A Roy, Y Wang, A Stanfill… - BMC Medical …, 2020 - Springer
Background Obesity is common among kidney transplant recipients; However biological
mediators of obesity are not well understood in this population. Because subcutaneous …

Placental Gene Co-expression Network for Maternal Plasma Lipids Revealed Enrichment of Inflammatory Response Pathways

M Ouidir, S Chatterjee, P Mendola, C Zhang… - Frontiers in …, 2021 - frontiersin.org
Maternal dyslipidemia during pregnancy has been associated with suboptimal fetal growth
and increased cardiometabolic diseasse risk in offspring. Altered placental function driven …