Background The association between obesity and nonalcoholic fatty liver disease (NAFLD)
has not been fully quantified, and the magnitude of NAFLD risk associated with obesity is …

After being absorbed, drugs distribute in the body in part to reach target tissues, in part to be
disposed in tissues where they do not exert clinically-relevant effects. Therapeutically …

Spleen has been considered a neglected organ so far, even though is strictly linked to liver.
The spleen plays an important role in the modulation of the immune system and in the …

This study evaluated if vitamin E consumption affects gut microbiota. Mice were grouped into
control, low vitamin E (LV), and high vitamin E (HV). LV and HV were fed DL-α-tocopherol at …

Chronic low-grade systemic inflammation represents a mechanism common to many
diseases linked to atherosclerosis-related pathways. There is a growing body of evidence …

Background Periodontitis is a chronic multifactorial inflammatory disease. Porphyromonas
gingivalis is a primary periopathogen in the initiation and development of periodontal …

The present study aimed to investigate whether melatonin (MT) treatment can attenuate
immunotoxicity induced by aluminum chloride (AlCl 3) in rat spleen. Forty-eight healthy male …

Periodontal disease is a chronic inflammatory disease of the jaws and is more prevalent in
obesity. Local and systemic oxidative stress may be an early link between periodontal …

A Western diet induces insulin resistance, liver steatosis (non-alcoholic fatty liver disease
(NAFLD)) and intestinal dysbiosis, leading to increased gut permeability and bacterial …

Context Bisphenol A, one of the highest‐volume chemicals currently available, is known to
act as endocrine disruptor and alters several metabolic functions, including inflammatory …