Despite daily fasting and feeding, plasma glucose levels are normally maintained within a
narrow range owing to the hormones insulin and glucagon. Insulin increases glucose …

Facilitative glucose transport is mediated by members of the Glut protein family that belong
to a much larger superfamily of 12 transmembrane segment transporters. Six members of …

In this review we summarize the present state of knowledge of the currently identified
members of the glucose transporter family, propose a basis for their diversity highlighting …

Gaps remain in our understanding of the precise molecular mechanisms by which insulin
regulates glucose uptake in fat and muscle cells. Recent evidence suggests that insulin …

Mammalian cells depend on glucose as a major substrate for energy production. Glucose is
transported into the cell via facilitative glucose transporters (GLUT) present in all cell types …

Despite remarkable progress in dissecting the signaling pathways that are crucial for the
metabolic effects of insulin, the molecular basis for the specificity of its cellular actions is not …

The acute effects of contraction and insulin on the glucose transport and GLUT4 glucose
transporter translocation were investigated in rat soleus muscles by using a 3-O …

Type 2 diabetes is a complex disorder with diminished insulin secretion and insulin action
contributing to the hyperglycemia and wide range of metabolic defects that underlie the …

Since the discovery of insulin roughly 80 yr ago, much has been learned about how target
cells receive, interpret, and respond to this peptide hormone. For example, we now know …

Nitrogen is the mineral nutrient that plants need in the greatest quantities and the one that
most frequently limits plant growth and crop yields. Most plants get their nitrogen (N) from the …