Acute stroke management practices in rural areas of the United States are suboptimal, which
creates an unacceptable health disparity between urban patients with stroke and their rural …

Background Informed consent is one of the cornerstones of biomedical research with human
subjects. Research ethics committees may allow for a modification or a waiver of consent …

Background Whether brain imaging can identify patients who are most likely to benefit from
therapies for acute ischemic stroke and whether endovascular thrombectomy improves …

Background: Cardiac arrest causes devastating neurological morbidity and mortality.
Mild/moderate hypothermia is neuroprotective after global cerebral ischemia. More rapid …

BACKGROUND: Optimal blood pressure (BP) management during endovascular stroke
treatment is not well established. We studied whether an individualized approach for …

Emergency research studies are high-stakes studies that are usually performed on the
sickest patients, where many patients or guardians have no opportunity to provide full …

Purpose In this series of articles—Research Ethics I, Research Ethics II, and Research
Ethics III—the authors provide a comprehensive review of the 9 core domains for the …

Background and Purpose—The ESCAPE trial (The Endovascular Treatment for Small Core
and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to …

Resumen ZUNIGA, Carol y ZUNIGA-HERNANDEZ, Jessica. Excepciones al uso del
consentimiento informado en investigación:¿ cuándo es esto posible en Chile?. Rev. méd …

Intravenous thrombolysis with recombinant tissue plasminogen activator is the standard of
care for the treatment of acute ischemic stroke within 3 hours after stroke onset. Randomized …