Mesenchymal stem cells (MSCs) are known for being multi-potent. However, they also
possess anticancer properties, which has prompted efforts to adapt MSCs for anticancer …

The bone marrow (BM) microenvironment regulates the properties of healthy hematopoietic
stem cells (HSCs) localized in specific niches. Two distinct microenvironmental niches have …

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood malignancy that arises
from the clonal expansion of transformed T-cell precursors. Although T-ALL prognosis has …

Abstract Melodinus cochinchinensis (Lour.) Merr. is a Yunnan endemic folk medicine. Our
previous study showed that 11-methoxytabersonine (11-MT) isolated from M …

Acute lymphoblastic leukemia with the worst prognosis is related to minimal residual
disease. Minimal residual disease not only depends on the individual peculiarities of …

We investigated if the antileukemic drug idarubicin induces autophagy, a process of
programmed cellular self-digestion, in leukemic cell lines and primary leukemic cells …

Although the treatment of adult T-cell acute lymphoblastic leukemia (T-ALL) has been
significantly improved, the heterogeneous genetic landscape of the disease often causes …

Current therapies for childhood T-cell acute lymphoblastic leukemia have increased survival
rates to above 85% in developed countries. Unfortunately, some patients fail to respond to …

Human T lymphotropic virus type 1 (HTLV‐1) infection can cause adult T‐cell lymphoblastic
leukemia (ATLL), an incurable, chemotherapy‐resistant malignancy. In a quest for new …

T-cell acute lymphoblastic leukemia (T-ALL) is a heterogeneous neoplastic disorder of
immature hematopoietic precursors committed to the T-cell lineage. T-ALL comprises about …