Macro‐and microvascular endothelial dysfunction in diabetes: 糖尿病诱导的内皮细胞功能损伤
Y Shi, PM Vanhoutte - Journal of diabetes, 2017 - Wiley Online Library
血管内皮细胞和内皮细胞释放的活性因子是调控血管舒张功能的重要因素. 糖尿病是慢性心血管
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …
Vitamin C and cardiovascular disease: an update
MB Morelli, J Gambardella, V Castellanos, V Trimarco… - Antioxidants, 2020 - mdpi.com
The potential beneficial effects of the antioxidant properties of vitamin C have been
investigated in a number of pathological conditions. In this review, we assess both clinical …
investigated in a number of pathological conditions. In this review, we assess both clinical …
Oxidative stress as the main target in diabetic retinopathy pathophysiology
OM Cecilia, CG José Alberto, NP José… - Journal of diabetes …, 2019 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus
(DM) causing vision impairment even at young ages. There are numerous mechanisms …
(DM) causing vision impairment even at young ages. There are numerous mechanisms …
Epigenomics in aortic dissection: From mechanism to therapeutics
Y Tao, G Li, Y Yang, Z Wang, S Wang, X Li, T Yu, X Fu - Life Sciences, 2023 - Elsevier
Aortic dissection (AD) has an unfavorable prognosis. It requires early diagnosis, appropriate
treatment strategies, and suspicion to recognize symptoms; thus, it is commonly described …
treatment strategies, and suspicion to recognize symptoms; thus, it is commonly described …
Adjuvant therapies in diabetic retinopathy as an early approach to delay its progression: the importance of oxidative stress and inflammation
RR Robles-Rivera… - Oxidative medicine …, 2020 - Wiley Online Library
Diabetes mellitus (DM) is a progressive disease induced by a sustained state of chronic
hyperglycemia that can lead to several complications targeting highly metabolic cells …
hyperglycemia that can lead to several complications targeting highly metabolic cells …
Ascorbic acid attenuates endothelial permeability triggered by cell-free hemoglobin
JL Kuck, JA Bastarache, CM Shaver, JP Fessel… - Biochemical and …, 2018 - Elsevier
Background Increased endothelial permeability is central to shock and organ dysfunction in
sepsis but therapeutics targeted to known mediators of increased endothelial permeability …
sepsis but therapeutics targeted to known mediators of increased endothelial permeability …
Transcriptional correlates of tolerance and lethality in mice predict Ebola virus disease patient outcomes
A Price, A Okumura, E Haddock, F Feldmann… - Cell reports, 2020 - cell.com
Host response to infection is a major determinant of disease severity in Ebola virus disease
(EVD), but gene expression programs associated with outcome are poorly characterized …
(EVD), but gene expression programs associated with outcome are poorly characterized …
Targeting the epigenome in in-stent restenosis: from mechanisms to therapy
X Yang, Y Yang, J Guo, Y Meng, M Li, P Yang… - … Therapy-Nucleic Acids, 2021 - cell.com
Coronary artery disease (CAD) is one of the most common causes of death worldwide. The
introduction of percutaneous revascularization has revolutionized the therapy of patients …
introduction of percutaneous revascularization has revolutionized the therapy of patients …
Pharmacotherapy and nutritional supplements for neovascular eye diseases
D Rusciano, P Bagnoli - Medicina, 2023 - mdpi.com
In this review, we aim to provide an overview of the recent findings about the treatment of
neovascular retinal diseases. The use of conventional drugs and nutraceuticals endowed …
neovascular retinal diseases. The use of conventional drugs and nutraceuticals endowed …
The use of nutraceuticals to counteract atherosclerosis: the role of the notch pathway
G Aquila, L Marracino, V Martino… - Oxidative medicine …, 2019 - Wiley Online Library
Despite the currently available pharmacotherapies, today, thirty percent of worldwide deaths
are due to cardiovascular diseases (CVDs), whose primary cause is atherosclerosis, an …
are due to cardiovascular diseases (CVDs), whose primary cause is atherosclerosis, an …