Nitric Oxide (NO) is a soluble endogenous gas with various biological functions like
signaling, and working as an effector molecule or metabolic regulator. In response to …

Rab proteins are generally required for transport vesicle docking. We have exploited yeast
secretion mutants to demonstrate that a rab protein is required for v-SNAREs and t-SNAREs …

With a molecular weight of 30 nitric oxide (NO) 1 is certainly one of the smallest biological
molecular mediators. In mammalian cells, NO is produced along with l-citrulline by the …

The Ob gene product, leptin, is an adipocyte-secreted hormone that centrally regulates
weight control. However, leptin receptor is expressed not only in the central nervous system …

NITRIC oxide (NO) is important in many biological functions1–5. It is generated from L-
arginine by the enzyme NO synthase (NOS). The cytokine-inducible NOS (iNOS) is activated …

MANY viruses have evolved mechanisms to avoid detection by the host immune system.
Herpes simplex virus (HSV) expresses an immediate early protein, ICP47, which blocks …

CD69 is an early leukocyte activation molecule expressed at sites of chronic inflammation.
The precise role of CD69 in immunity has not been elucidated owing to the absence of a …

The high-output pathway of nitric oxide production helps protect mice from infection by
several pathogens, including Mycobacterium tuberculosis. However, based on studies of …

Leptin is a an adipocyte-secreted hormone that regulates weight centrally. However, the
leptin receptor is expressed not only in the central nervous system, but also in peripheral …

Inducible synthesis of nitric oxide (NO) by macrophages is an important mechanism of the
host defense against intracellular infection in mice, but the evidence for significant levels of …