Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

Photoclick chemistry: a bright idea

BD Fairbanks, LJ Macdougall, S Mavila, J Sinha… - Chemical …, 2021 - ACS Publications
At its basic conceptualization, photoclick chemistry embodies a collection of click reactions
that are performed via the application of light. The emergence of this concept has had …

Extracellular‐matrix‐reinforced bioinks for 3D bioprinting human tissue

MM De Santis, HN Alsafadi, S Tas… - Advanced …, 2021 - Wiley Online Library
Recent advances in 3D bioprinting allow for generating intricate structures with dimensions
relevant for human tissue, but suitable bioinks for producing translationally relevant tissue …

Novel drug delivery systems and disease models for pulmonary fibrosis

R Li, Y Jia, X Kong, Y Nie, Y Deng, Y Liu - Journal of Controlled Release, 2022 - Elsevier
Pulmonary fibrosis (PF) is a serious and progressive lung disease which is possibly life-
threatening. It causes lung scarring and affects lung functions including epithelial cell injury …

[HTML][HTML] Engineering the extracellular matrix for organoid culture

JH Heo, D Kang, SJ Seo, Y Jin - International Journal of …, 2022 - synapse.koreamed.org
Organoids show great potential in clinical translational research owing to their intriguing
properties to represent a near physiological model for native tissues. However, the …

3D bioprinting strategies, challenges, and opportunities to model the lung tissue microenvironment and its function

M Barreiro Carpio, M Dabaghi, J Ungureanu… - … in Bioengineering and …, 2021 - frontiersin.org
Human lungs are organs with an intricate hierarchical structure and complex composition;
lungs also present heterogeneous mechanical properties that impose dynamic stress on …

Chemical modification of human decellularized extracellular matrix for incorporation into phototunable hybrid-hydrogel models of tissue fibrosis

RS Hewawasam, R Blomberg… - … applied materials & …, 2023 - ACS Publications
Tissue fibrosis remains a serious health condition with high morbidity and mortality rates.
There is a critical need to engineer model systems that better recapitulate the spatial and …

Decellularised scaffolds: just a framework? Current knowledge and future directions

E García-Gareta, Y Abduldaiem… - Journal of Tissue …, 2020 - journals.sagepub.com
The use of decellularised matrices as scaffolds offers the advantage of great similarity with
the tissue to be replaced. Moreover, decellularised tissues and organs can be repopulated …

[HTML][HTML] Advances of microfluidic lung chips for assessing atmospheric pollutants exposure

H Wang, F Yin, Z Li, W Su, D Li - Environment International, 2023 - Elsevier
Atmospheric pollutants, including particulate matters, nanoparticles, bioaerosols, and some
chemicals, have posed serious threats to the environment and the human's health. The …

[HTML][HTML] An in vitro model of fibrosis using crosslinked native extracellular matrix-derived hydrogels to modulate biomechanics without changing composition

M Nizamoglu, RHJ de Hilster, F Zhao, PK Sharma… - Acta biomaterialia, 2022 - Elsevier
Extracellular matrix (ECM) is a dynamic network of proteins, proteoglycans and
glycosaminoglycans, providing structure to the tissue and biochemical and biomechanical …