Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
Photoclick chemistry: a bright idea
At its basic conceptualization, photoclick chemistry embodies a collection of click reactions
that are performed via the application of light. The emergence of this concept has had …
that are performed via the application of light. The emergence of this concept has had …
Extracellular‐matrix‐reinforced bioinks for 3D bioprinting human tissue
Recent advances in 3D bioprinting allow for generating intricate structures with dimensions
relevant for human tissue, but suitable bioinks for producing translationally relevant tissue …
relevant for human tissue, but suitable bioinks for producing translationally relevant tissue …
Novel drug delivery systems and disease models for pulmonary fibrosis
R Li, Y Jia, X Kong, Y Nie, Y Deng, Y Liu - Journal of Controlled Release, 2022 - Elsevier
Pulmonary fibrosis (PF) is a serious and progressive lung disease which is possibly life-
threatening. It causes lung scarring and affects lung functions including epithelial cell injury …
threatening. It causes lung scarring and affects lung functions including epithelial cell injury …
[HTML][HTML] Engineering the extracellular matrix for organoid culture
JH Heo, D Kang, SJ Seo, Y Jin - International Journal of …, 2022 - synapse.koreamed.org
Organoids show great potential in clinical translational research owing to their intriguing
properties to represent a near physiological model for native tissues. However, the …
properties to represent a near physiological model for native tissues. However, the …
3D bioprinting strategies, challenges, and opportunities to model the lung tissue microenvironment and its function
M Barreiro Carpio, M Dabaghi, J Ungureanu… - … in Bioengineering and …, 2021 - frontiersin.org
Human lungs are organs with an intricate hierarchical structure and complex composition;
lungs also present heterogeneous mechanical properties that impose dynamic stress on …
lungs also present heterogeneous mechanical properties that impose dynamic stress on …
Chemical modification of human decellularized extracellular matrix for incorporation into phototunable hybrid-hydrogel models of tissue fibrosis
RS Hewawasam, R Blomberg… - … applied materials & …, 2023 - ACS Publications
Tissue fibrosis remains a serious health condition with high morbidity and mortality rates.
There is a critical need to engineer model systems that better recapitulate the spatial and …
There is a critical need to engineer model systems that better recapitulate the spatial and …
Decellularised scaffolds: just a framework? Current knowledge and future directions
E García-Gareta, Y Abduldaiem… - Journal of Tissue …, 2020 - journals.sagepub.com
The use of decellularised matrices as scaffolds offers the advantage of great similarity with
the tissue to be replaced. Moreover, decellularised tissues and organs can be repopulated …
the tissue to be replaced. Moreover, decellularised tissues and organs can be repopulated …
[HTML][HTML] Advances of microfluidic lung chips for assessing atmospheric pollutants exposure
Atmospheric pollutants, including particulate matters, nanoparticles, bioaerosols, and some
chemicals, have posed serious threats to the environment and the human's health. The …
chemicals, have posed serious threats to the environment and the human's health. The …
[HTML][HTML] An in vitro model of fibrosis using crosslinked native extracellular matrix-derived hydrogels to modulate biomechanics without changing composition
Extracellular matrix (ECM) is a dynamic network of proteins, proteoglycans and
glycosaminoglycans, providing structure to the tissue and biochemical and biomechanical …
glycosaminoglycans, providing structure to the tissue and biochemical and biomechanical …