DNA nanostructures interacting with lipid bilayer membranes
M Langecker, V Arnaut, J List… - Accounts of chemical …, 2014 - ACS Publications
Conspectus DNA has been previously shown to be useful as a material for the fabrication of
static nanoscale objects, and also for the realization of dynamic molecular devices and …
static nanoscale objects, and also for the realization of dynamic molecular devices and …
Nucleic acid amphiphiles: synthesis, properties, and applications
A Gubu, X Zhang, A Lu, B Zhang, Y Ma… - … Therapy-Nucleic Acids, 2023 - cell.com
Nucleic acid amphiphiles, referring to nucleic acids modified with large hydrophobic groups,
have been widely used in programmable bioengineering. Since nucleic acids are …
have been widely used in programmable bioengineering. Since nucleic acids are …
Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression
Nanotechnology offers many benefits, and here we report an advantage of applying RNA
nanotechnology for directional control. The orientation of arrow-shaped RNA was altered to …
nanotechnology for directional control. The orientation of arrow-shaped RNA was altered to …
Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy
J Zhuang, J Tan, C Wu, J Zhang, T Liu… - Nucleic acids …, 2020 - academic.oup.com
Extracellular vesicles (EVs) hold great promise for transporting CRISPR–Cas9 RNA-guided
endonucleases (RNP) throughout the body. However, the cell-selective delivery of EVs is …
endonucleases (RNP) throughout the body. However, the cell-selective delivery of EVs is …
A quantitative assessment of the dynamic modification of lipid–DNA probes on live cell membranes
Synthetic lipid–DNA probes have recently attracted much attention for cell membrane
analysis, transmembrane signal transduction, and regulating intercellular networks. These …
analysis, transmembrane signal transduction, and regulating intercellular networks. These …
DNA nanostructures on membranes as tools for synthetic biology
Over the last decade, functionally designed DNA nanostructures applied to lipid membranes
prompted important achievements in the fields of biophysics and synthetic biology. Taking …
prompted important achievements in the fields of biophysics and synthetic biology. Taking …
Hybrid lipid oligonucleotide conjugates: synthesis, self-assemblies and biomedical applications
A Patwa, A Gissot, I Bestel, P Barthélémy - Chemical Society Reviews, 2011 - pubs.rsc.org
Hybrid lipid oligonucleotide conjugates: synthesis, self-assemblies and biomedical applications -
Chemical Society Reviews (RSC Publishing) DOI:10.1039/C1CS15038C Royal Society of …
Chemical Society Reviews (RSC Publishing) DOI:10.1039/C1CS15038C Royal Society of …
Quantifying tensile forces at cell–cell junctions with a DNA-based fluorescent probe
Cells are physically contacting with each other. Direct and precise quantification of forces at
cell–cell junctions is still challenging. Herein, we have developed a DNA-based ratiometric …
cell–cell junctions is still challenging. Herein, we have developed a DNA-based ratiometric …
Quantification of multivalent interactions by tracking single biological nanoparticle mobility on a lipid membrane
Macromolecular association commonly occurs via dynamic engagement of multiple weak
bonds referred to as multivalent interactions. The distribution of the number of bonds …
bonds referred to as multivalent interactions. The distribution of the number of bonds …
Switchable domain partitioning and diffusion of DNA origami rods on membranes
Recently, DNA origami became a powerful tool for custom-shaped functional biomolecules.
In this paper, we present the first approach towards assembling amphipathic three …
In this paper, we present the first approach towards assembling amphipathic three …