Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

Conspectus Metal ions have been identified as key factors modulating the aggregation of
amyloid-β peptide (Aβ) implicated in Alzheimer's disease (AD). The presence of elevated …

Metal ions, such as copper and zinc ions, have been shown to strongly modulate the self-
assembly of the amyloid-β (Aβ) peptide into insoluble fibrils, and elevated concentrations of …

This narrative review summarises the evidence for considering physical exercise (PE) as a
non-pharmacological intervention for delaying cognitive decline in patients with Alzheimer's …

The concept of developing novel anti-amyloid inhibitors in the scientific community has
engrossed remarkable research interests and embraced significant potential to resolve …

Amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease and similar
neurodegenerative disorders take their toll on patients, caregivers and society. A common …

Although the pathogenesis of Alzheimer's disease (AD) is still unclear, abnormally high
concentrations of metal ions, like copper, iron and zinc, were found in senile plaques of AD …

Apolipoproteins co-deposit with amyloids, yet apolipoprotein–amyloid interactions are
enigmatic. To understand how apoE interacts with Alzheimer's amyloid-β (Aβ) peptide in …

Amyloidosis is a deleterious condition caused by abnormal amyloid fibril build-up in living
tissues. To date, 42 proteins that are linked to amyloid fibrils have been discovered. Amyloid …

Uranium (U) is naturally present in ambient air, water, and soil, and depleted uranium (DU)
is released into the environment via industrial and military activities. While the radiological …