[HTML][HTML] Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds
G Zhu, T Zhang, M Chen, K Yao, X Huang, B Zhang… - Bioactive materials, 2021 - Elsevier
Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …
approaches, autologous and allogeneic bone grafting have not achieved the ideal …
A review on the use of computational methods to characterize, design, and optimize tissue engineering scaffolds, with a potential in 3D printing fabrication
S Zhang, S Vijayavenkataraman… - Journal of Biomedical …, 2019 - Wiley Online Library
The design and fabrication of tissue engineering scaffolds is a highly complex process. In
order to provide a proper architecture for cells to grow, proliferate, and differentiate to form …
order to provide a proper architecture for cells to grow, proliferate, and differentiate to form …
Mechanical performance of highly permeable laser melted Ti6Al4V bone scaffolds
Critically engineered stiffness and strength of a scaffold are crucial for managing
maladapted stress concentration and reducing stress shielding. At the same time, suitable …
maladapted stress concentration and reducing stress shielding. At the same time, suitable …
Finite element analysis of mechanical behavior, permeability and fluid induced wall shear stress of high porosity scaffolds with gyroid and lattice-based architectures
D Ali, S Sen - Journal of the mechanical behavior of biomedical …, 2017 - Elsevier
Scaffold design necessitates the consideration of mechanical properties and fluid flow
dynamics as the main factors in the development of such materials. The mechanical …
dynamics as the main factors in the development of such materials. The mechanical …
Direct writing electrospinning of scaffolds with multidimensional fiber architecture for hierarchical tissue engineering
H Chen, ABFB Malheiro, C van Blitterswijk… - … Applied Materials & …, 2017 - ACS Publications
Nanofibrous structures have long been used as scaffolds for tissue engineering (TE)
applications, due to their favorable characteristics, such as high porosity, flexibility, high cell …
applications, due to their favorable characteristics, such as high porosity, flexibility, high cell …
[HTML][HTML] Recent advances in bioreactors for cell-based therapies
M Stephenson, W Grayson - F1000Research, 2018 - ncbi.nlm.nih.gov
Bioreactors have become indispensable tools in the cell-based therapy industry. Various
forms of bioreactors are used to maintain well-controlled microenvironments to regulate cell …
forms of bioreactors are used to maintain well-controlled microenvironments to regulate cell …
[HTML][HTML] Multiscale modeling of bone tissue mechanobiology
Mechanical environment has a crucial role in our organism at the different levels, ranging
from cells to tissues and our own organs. This regulatory role is especially relevant for …
from cells to tissues and our own organs. This regulatory role is especially relevant for …
Finite element evaluations of the mechanical properties of polycaprolactone/hydroxyapatite scaffolds by direct ink writing: Effects of pore geometry
Osteochondral (OC) defects usually involve the damage of both the cartilage and its
underneath subchondral bone. In recent years, tissue engineering (TE) has become the …
underneath subchondral bone. In recent years, tissue engineering (TE) has become the …
Permeability and fluid flow-induced wall shear stress of bone tissue scaffolds: Computational fluid dynamic analysis using Newtonian and non-Newtonian blood flow …
D Ali, S Sen - Computers in biology and medicine, 2018 - Elsevier
Among the factors that are important in successful bone tissue regeneration through
scaffolds are permeability and fluid flow-induced wall shear stress (WSS) because of the …
scaffolds are permeability and fluid flow-induced wall shear stress (WSS) because of the …
Boosting bone regeneration using augmented melt-extruded additive-manufactured scaffolds
Bone tissue engineering (BTE) is in active search of the ideal scaffold to give a clinical
solution for bone regeneration in non-union fractures. During the last decades, the use of …
solution for bone regeneration in non-union fractures. During the last decades, the use of …