Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission
Executive summary Every infant, child, and adolescent will experience pain at times
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …
Early neonatal pain—a review of clinical and experimental implications on painful conditions later in life
MD Williams, BDX Lascelles - Frontiers in pediatrics, 2020 - frontiersin.org
Modern health care has brought our society innumerable benefits but has also introduced
the experience of pain very early in life. For example, it is now routine care for newborns to …
the experience of pain very early in life. For example, it is now routine care for newborns to …
Long-term effects of neonatal pain
SM Walker - Seminars in Fetal and Neonatal Medicine, 2019 - Elsevier
Pain experienced during neonatal intensive care management can influence
neurodevelopmental outcome and the somatosensory and/or emotional components of pain …
neurodevelopmental outcome and the somatosensory and/or emotional components of pain …
Neuroimaging-based biomarkers for pain: state of the field and current directions
Chronic pain is an endemic problem involving both peripheral and brain pathophysiology.
Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have …
Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have …
[HTML][HTML] The effect of disbudding age on healing and pain sensitivity in dairy calves
SJJ Adcock, CB Tucker - Journal of dairy science, 2018 - Elsevier
Hot-iron disbudding, a husbandry procedure performed in dairy calves in which horn bud
growth is prevented through tissue cauterization, produces severe burns. Little is known …
growth is prevented through tissue cauterization, produces severe burns. Little is known …
[HTML][HTML] Somatosensory function and pain in extremely preterm young adults from the UK EPICure cohort: sex-dependent differences and impact of neonatal surgery
SM Walker, A Melbourne, H O'Reilly… - British journal of …, 2018 - Elsevier
Background Surgery or multiple procedural interventions in extremely preterm neonates
influence neurodevelopmental outcome and may be associated with long-term changes in …
influence neurodevelopmental outcome and may be associated with long-term changes in …
Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?
In 2006, humans with a congenital insensitivity to pain (CIP) were found to lack functional
NaV1. 7 channels. In the subsequent 15 years there was a rush to develop selective …
NaV1. 7 channels. In the subsequent 15 years there was a rush to develop selective …
The development of the nociceptive brain
This review addresses the fundamental question of how we first experience pain, at the
beginning of our lives. The brain is activated by peripheral tissue damaging stimulation from …
beginning of our lives. The brain is activated by peripheral tissue damaging stimulation from …
Defining pain in newborns: need for a uniform taxonomy?
KJS Anand - Acta Paediatrica, 2017 - Wiley Online Library
A framework for defining pain terms such as acute, persistent, prolonged or chronic pain to
newborns was derived from the scientific literature on neonatal pain assessments, previous …
newborns was derived from the scientific literature on neonatal pain assessments, previous …
[HTML][HTML] Oral administration of berberine limits post-traumatic osteoarthritis development and associated pain via AMP-activated protein kinase (AMPK) in mice
Objective We investigated the effect of berberine, a natural plant product that can activate
AMP-activated protein kinase (AMPK), on Osteoarthritis (OA) development and associated …
AMP-activated protein kinase (AMPK), on Osteoarthritis (OA) development and associated …