The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection has posed the world at a pandemic risk. Coronavirus-19 disease (COVID-19) is an …

Abacavir is a carbocyclic 2′-deoxyguanosine nucleoside reverse transcriptase inhibitor
that is used as either a 600-mg once-daily or 300-mg twice-daily regimen exclusively in the …

Background. A novel translational pharmacology investigation was conducted by combining
an in vitro efficacy target with mucosal tissue pharmacokinetic (PK) data and mathematical …

Infection with HIV persists despite suppressive antiretroviral therapy (ART), and treatment
interruption results in rapid viral rebound. Antibody-mediated CD8+ lymphocyte depletion in …

Several lines of evidence point to kidney disease as an important complication of human
immunodeficiency virus (HIV) infection. Kidney function is abnormal in up to 30% of HIV …

Background. Polyoma BK virus produces an aggressively destructive nephropathy in
approximately 3% to 8% of renal allografts, is associated with graft loss within one year in …

HIV infection is associated with a state of chronic, generalized immune activation that has
been shown in many studies to be a key predictor of progression to AIDS. Consistent with …

These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the management of transplantation in HIV …

Feminizing hormone therapy (FHT) may interact with human immunodeficiency virus
preexposure prophylaxis (PrEP). We found that transgender women who took FHT exhibited …

Stable remission is the ultimate goal of HIV therapy. A review of recent studies on the ability
of HIV to persist despite highly active antiretroviral therapy (HAART) and immune stimulation …