Autonomic Nervous System Dysfunction: JACC Focus Seminar

JJ Goldberger, R Arora, U Buckley… - Journal of the American …, 2019 - jacc.org
Autonomic nervous system control of the heart is a dynamic process in both health and
disease. A multilevel neural network is responsible for control of chronotropy, lusitropy …

The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies

N Herring, M Kalla, DJ Paterson - Nature Reviews Cardiology, 2019 - nature.com
Research into cardiac autonomic control has received great interest in the past 20 years,
and we are now at a critical juncture with regard to the clinical translation of the experimental …

Translational neurocardiology: preclinical models and cardioneural integrative aspects

JL Ardell, MC Andresen, JA Armour… - The Journal of …, 2016 - Wiley Online Library
Neuronal elements distributed throughout the cardiac nervous system, from the level of the
insular cortex to the intrinsic cardiac nervous system, are in constant communication with …

Baroreflex activation therapy with the Barostim™ device in patients with heart failure with reduced ejection fraction: a patient level meta‐analysis of randomized …

AJS Coats, WT Abraham, MR Zile… - European Journal of …, 2022 - Wiley Online Library
Aims Heart failure with reduced ejection fraction (HFrEF) remains associated with high
morbidity and mortality, poor quality of life (QoL) and significant exercise limitation …

Normalization of blood pressure with spinal cord epidural stimulation after severe spinal cord injury

SJ Harkema, S Wang, CA Angeli, Y Chen… - Frontiers in human …, 2018 - frontiersin.org
Chronic low blood pressure and orthostatic hypotension remain challenging clinical issues
after severe spinal cord injury (SCI), affecting health, rehabilitation, and quality of life. We …

The role of the autonomic nervous system in arrhythmias and sudden cardiac death

S Franciosi, FKG Perry, TM Roston, KR Armstrong… - Autonomic …, 2017 - Elsevier
The autonomic nervous system (ANS) is complex and plays an important role in cardiac
arrhythmia pathogenesis. A deeper understanding of the anatomy and development of the …

Research opportunities in autonomic neural mechanisms of cardiopulmonary regulation: a report from the national heart, lung, and blood institute and the national …

R Mehra, OA Tjurmina, OA Ajijola, R Arora… - Basic to Translational …, 2022 - jacc.org
This virtual workshop was convened by the National Heart, Lung, and Blood Institute, in
partnership with the Office of Strategic Coordination of the Office of the National Institutes of …

Autonomic modulation of cardiac arrhythmias: methods to assess treatment and outcomes

S Stavrakis, K Kulkarni, JP Singh, DG Katritsis… - Clinical …, 2020 - jacc.org
The autonomic nervous system plays a central role in the pathogenesis of multiple cardiac
arrhythmias, including atrial fibrillation and ventricular tachycardia. As such, autonomic …

Electroceutical targeting of the autonomic nervous system

CC Horn, JL Ardell, LE Fisher - Physiology, 2019 - journals.physiology.org
Autonomic nerves are attractive targets for medical therapies using electroceutical devices
because of the potential for selective control and few side effects. These devices use novel …

The sympathetic innervation of the heart: Important new insights

JH Coote, RA Chauhan - Autonomic Neuroscience, 2016 - Elsevier
Autonomic control of the heart has a significant influence over development of life
threatening arrhythmias that can lead to sudden cardiac death. Sympathetic activity is known …