The biology and rationale of targeting nectin-4 in urothelial carcinoma
EI Heath, JE Rosenberg - Nature Reviews Urology, 2021 - nature.com
Bladder cancer is the tenth most common cancer type worldwide. Urothelial carcinoma is the
most common type of bladder cancer and accounts for 90% of bladder cancer cases in the …
most common type of bladder cancer and accounts for 90% of bladder cancer cases in the …
Prognostic and prediction tools in bladder cancer: a comprehensive review of the literature
Context This review focuses on risk assessment and prediction tools for bladder cancer
(BCa). Objective To review the current knowledge on risk assessment and prediction tools to …
(BCa). Objective To review the current knowledge on risk assessment and prediction tools to …
Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
Z Chen, L Zhou, L Liu, Y Hou, M Xiong, Y Yang… - Nature …, 2020 - nature.com
Although substantial progress has been made in cancer biology and treatment, clinical
outcomes of bladder carcinoma (BC) patients are still not satisfactory. The tumor …
outcomes of bladder carcinoma (BC) patients are still not satisfactory. The tumor …
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
JS Damrauer, KA Hoadley, DD Chism… - Proceedings of the …, 2014 - National Acad Sciences
We sought to define whether there are intrinsic molecular subtypes of high-grade bladder
cancer. Consensus clustering performed on gene expression data from a meta-dataset of …
cancer. Consensus clustering performed on gene expression data from a meta-dataset of …
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy
MM Tu, HA Abdel-Hafiz, RT Jones, A Jean… - Communications …, 2020 - nature.com
Immunotherapies targeting the PD-1/PD-L1 axis are now a mainstay in the clinical
management of multiple cancer types, however, many tumors still fail to respond. CCL2 is …
management of multiple cancer types, however, many tumors still fail to respond. CCL2 is …
Computational recognition of lncRNA signature of tumor-infiltrating B lymphocytes with potential implications in prognosis and immunotherapy of bladder cancer
Long noncoding RNAs (lncRNAs) have been associated with cancer immunity regulation
and the tumor microenvironment (TME). However, functions of lncRNAs of tumor-infiltrating …
and the tumor microenvironment (TME). However, functions of lncRNAs of tumor-infiltrating …
EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype
S Rebouissou, I Bernard-Pierrot… - Science translational …, 2014 - science.org
Muscle-invasive bladder carcinoma (MIBC) constitutes a heterogeneous group of tumors
with a poor outcome. Molecular stratification of MIBC may identify clinically relevant tumor …
with a poor outcome. Molecular stratification of MIBC may identify clinically relevant tumor …
Integrated multiomics analysis and machine learning refine molecular subtypes and prognosis for muscle-invasive urothelial cancer
G Chu, X Ji, Y Wang, H Niu - Molecular Therapy-Nucleic Acids, 2023 - cell.com
Muscle-invasive urothelial cancer (MUC), characterized by high aggressiveness and
significant heterogeneity, is currently lacking highly precise individualized treatment options …
significant heterogeneity, is currently lacking highly precise individualized treatment options …
Modelling bladder cancer in mice: opportunities and challenges
T Kobayashi, TB Owczarek, JM McKiernan… - Nature reviews …, 2015 - nature.com
The prognosis and treatment of bladder cancer have improved little in the past 20 years.
Bladder cancer remains a debilitating and often fatal disease, and is among the most costly …
Bladder cancer remains a debilitating and often fatal disease, and is among the most costly …
[HTML][HTML] Systemic immune-inflammation index predicts prognosis of bladder cancer patients after radical cystectomy
W Zhang, R Wang, W Ma, Y Wu, N Maskey… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background The systemic immune-inflammation index (SII) has been used as a prognostic
marker for several cancer types, but there is no in-depth study in bladder cancer. This study …
marker for several cancer types, but there is no in-depth study in bladder cancer. This study …