I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary …

The International Collaboration in Asthma, Allergy and Immunology initiated an international
coalition among the American Academy of Allergy, Asthma & Immunology; the European …

Background Activated phosphoinositide 3-kinase δ syndrome (APDS) is a recently
described combined immunodeficiency resulting from gain-of-function mutations in PIK3CD …

The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of
similar evidence based position papers published in 2005 and 2007. The document …

Background Common variable immunodeficiency (CVID) is an antibody deficiency with an
equal sex distribution and a high variability in clinical presentation. The main features …

Non-infectious complications in common variable immunodeficiency (CVID) have emerged
as a major clinical challenge. Detailed clinical spectrum, organ-specific pathologies and …

Background: The role of humoral immunity has been well established in reducing infection
risk and facilitating viral clearance in patients with COVID-19. However, the relationship …

The intestinal mucosa contains the largest population of antibody-secreting plasma cells in
the body, and in humans several grams of secretory immunoglobulin A (SIgA) are released …