Tuberculosis infection in pregnant people: Current practices and research priorities

JS Mathad, S Yadav, A Vaidyanathan, A Gupta… - Pathogens, 2022 - mdpi.com
Women are significantly more likely to develop tuberculosis (TB) disease within the first 90
days after pregnancy than any other time in their lives. Whether pregnancy increases risk of …

Tuberculosis in pregnancy

SYA Hui, TT Lao - Best Practice & Research Clinical Obstetrics & …, 2022 - Elsevier
Due to COVID-19 pandemic, the latest progress of the End Tuberculosis (TB) Strategy was
far from optimal and services for TB needs to be quickly restored. Pregnancy is a unique …

Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients

K Harling, E Adankwah, A Güler… - Cellular & molecular …, 2019 - nature.com
T-cells critically contribute to protection against Mycobacterium tuberculosis infection, and
impaired T-cell responses can lead to disease progression. Pro-inflammatory and …

Interferon gamma release assay and tuberculin skin test performance in pregnant women living with and without HIV

SR Kaplan, JN Escudero, J Mecha… - JAIDS Journal of …, 2022 - journals.lww.com
Background: HIV and pregnancy may affect latent TB infection (LTBI) diagnostics. Tuberculin
skin test (TST) and newer generation QuantiFERON-TB Gold Plus (QFT-Plus) evaluations in …

Determinants of QuantiFERON Plus-diagnosed tuberculosis infection in adult Ugandan TB contacts: A cross-sectional study

J Mayito, AR Martineau, D Tiwari, L Nakiyingi… - PloS one, 2023 - journals.plos.org
Background The tuberculin skin test is commonly used to diagnose latent tuberculosis
infection (LTBI) in resource-limited settings, but its specificity is limited by factors including …

Transcriptional analysis for tuberculosis in pregnant women from the PRegnancy Associated Changes In Tuberculosis Immunology (PRACHITi) study

JS Mathad, ATL Queiroz, R Bhosale… - Clinical Infectious …, 2022 - academic.oup.com
A new tuberculosis (TB) diagnostic cartridge assay, which detects a 3-gene TB signature in
whole blood, was not diagnostic in women with maternal TB disease in India (area under the …

Impact of Human Immunodeficiency Virus and Peripartum Period on Mycobacterium tuberculosis Infection Detection

JN Escudero, J Mecha, BA Richardson… - The Journal of …, 2023 - academic.oup.com
Background Pregnancy and human immunodeficiency virus (HIV) may influence
tuberculosis infection detection using interferon (IFN)-γ release assay (QFT-Plus; Qiagen) …

Efficacy and Risk Factors of Interferon-Gamma Release Assays among HIV-Positive Individuals

H Qin, Y Wang, L Huang, Y Huang, J Ye… - International Journal of …, 2023 - mdpi.com
Latent tuberculosis is prevalent in HIV-infected people and has an impact on the
progression of AIDS. The aim of this study is to match a more accurate IGRA method for the …

Tuberculin test versus interferon gamma release assay in pregnant women with household contacts of tuberculosis patients

MT Chalid, D Puspawaty, AM Tahir… - The International …, 2022 - journals.lww.com
Background: Pregnant women who live in tuberculosis (TB)-affected households are more
likely to develop latent TB infection (LTBI), which often escapes treatment. This study aims to …

Experience of an Egyptian tertiary Laboratory in the diagnosis of tuberculous and non-tuberculous Mycobacterial Infections: A five-year retrospective study.

AA Ramadan, SM Shawky, A Ibrahem… - Microbes and Infectious …, 2024 - journals.ekb.eg
Background: Tuberculosis (TB) is one of the significant health concerns in Egypt,
necessitating rapid, affordable, and accurate diagnosis to aid in its control. This study …