Assays of tongue force, timing, and dynamics in rat and mouse models

DM Rudisch, MN Krasko, AF Nisbet… - Brain research …, 2022 - Elsevier
Communication and swallowing are highly complex sensorimotor events that are tightly
linked to respiration and vital to health and well-being. The tongue is a complex organ, often …

Tongue function: an underrecognized component in the treatment of obstructive sleep apnea with mandibular repositioning appliance

W Wang, C Di, S Mona, L Wang… - Canadian Respiratory …, 2018 - Wiley Online Library
Obstructive sleep apnea (OSA) is a common but still underrecognized disorder. A
mandibular repositioning appliance (MRA) is used to treat OSA by advancing the mandible …

Age-related alterations in swallowing biomechanics

H Kletzien, MJ Cullins, NP Connor - Experimental gerontology, 2019 - Elsevier
Background Aging rodent models allow for the discovery of underlying mechanisms of
cranial muscle dysfunction. Methods are needed to allow quantification of complex …

Reduced tongue force and functional swallowing changes in a rat model of post stroke dysphagia

MJ Cullins, NP Connor - Brain research, 2019 - Elsevier
Purpose Dysphagia is a common problem after stroke that is often associated with tongue
weakness. However, the physiological mechanisms of post-stroke tongue muscle weakness …

Progressive protrusive tongue exercise does not alter aging effects in retrusive tongue muscles

TJ Glass, JE Figueroa, JA Russell, BN Krekeler… - Frontiers in …, 2021 - frontiersin.org
Purpose: Exercise-based treatment approaches for dysphagia may improve swallow
function in part by inducing adaptive changes to muscles involved in swallowing and …

Effects of tongue exercise frequency on tongue muscle biology and swallowing physiology in a rat model

BN Krekeler, JM Weycker, NP Connor - Dysphagia, 2020 - Springer
Age-related changes in muscle composition and function are often treated using exercise,
including muscles of the tongue to treat swallowing impairments (dysphagia). Although …

Dysphagia in Parkinson Disease: Part II—Current Treatment Options and Insights from Animal Research

MN Krasko, DM Rudisch, RJ Burdick… - … Physical Medicine and …, 2023 - Springer
Abstract Purpose of Review Dysphagia is highly prevalent in Parkinson disease (PD) but is
not typically identified nor treated until later in the disease process. This review summarizes …

Changes in ultrasonic vocalizations after unilateral cerebral ischemia in a rat stroke model

MJ Cullins, C Lenell, MR Ciucci, NP Connor - Behavioural brain research, 2023 - Elsevier
Stroke frequently results in communication impairments that negatively impact quality of life
and overall recovery, yet the biological mechanisms underlying these changes are not well …

Differential impact of tongue exercise on intrinsic lingual muscles

MJ Cullins, BN Krekeler, NP Connor - The Laryngoscope, 2018 - Wiley Online Library
Objectives/Hypothesis Aging is associated with muscle fiber hypotrophy and decreased
percentages of rapidly contracting myosin heavy chain (MyHC) type IIb muscle fibers …

Molecular biomarkers of dysphagia targeted exercise induced neuroplasticity: A review of mechanistic processes and preliminary data on detraining effects

R Krishnamurthy, C Krishnamoorthy, AM Dietsch… - Brain Research, 2024 - Elsevier
While molecular adaptations accompanying neuroplasticity during physical exercises are
well-established, little is known about adaptations during dysphagia-targeted exercises. This …