Although the manifestation of trauma in the body is a phenomenon well-endorsed by
clinicians and traumatized individuals, the neurobiological underpinnings of this …

Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Primates are long-lived, highly social mammals who maintain long-term social bonds and
cohesive social groups through many affiliative mechanisms, foremost among them social …

Receiving touch is of critical importance, as many studies have shown that touch promotes
mental and physical well-being. We conducted a pre-registered (PROSPERO …

Social touch—the affiliative skin-to-skin contact between individuals—can rapidly evoke
emotions of comfort, pleasure, or calm, and is essential for mental and physical well-being …

Comforting is a crucial form of prosocial behavior that is important for maintaining social
unity and improving the physical and emotional well-being of social species. It is often …

In anthropoid primates, social grooming is the principal mechanism (mediated by the central
nervous system endorphin system) that underpins social bonding. However, the time …

Highlights•Perception is inherently multisensory, and tactile perception is no
exception.•Sensory-discriminative and affective touch influenced by other senses.•To date …

Highlights•Social touch stimulates low-threshold C-fiber mechanoreceptors
(CLTMs).•Activation of CLTMs increases oxytocin release and leads to social …

Introduction Saffron, the dried stigmas of Crocus sativus L. is a famous and high-value
agricultural product of Iran exclusively used for cooking purpose and well known to treat …