Paxillin: A hub for mechano-transduction from the β3 integrin-talin-kindlin axis
M Ripamonti, B Wehrle-Haller… - Frontiers in Cell and …, 2022 - frontiersin.org
Focal adhesions are specialized integrin-dependent adhesion complexes, which ensure cell
anchoring to the extracellular matrix. Focal adhesions also function as mechano-signaling …
anchoring to the extracellular matrix. Focal adhesions also function as mechano-signaling …
miRCOVID-19: potential targets of human miRNAs in SARS-CoV-2 for RNA-based drug discovery
T Alam, L Lipovich - Non-coding RNA, 2021 - mdpi.com
Sense-antisense interactions of long and short RNAs in human cells are integral to post-
transcriptional gene regulation, in particular that of mRNAs by microRNAs. Many viruses …
transcriptional gene regulation, in particular that of mRNAs by microRNAs. Many viruses …
Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation
Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton
and transduce signals in response to both chemical and mechanical cues. The composition …
and transduce signals in response to both chemical and mechanical cues. The composition …
Deep learning in LncRNAome: contribution, challenges, and perspectives
Long non-coding RNAs (lncRNA), the pervasively transcribed part of the mammalian
genome, have played a significant role in changing our protein-centric view of genomes …
genome, have played a significant role in changing our protein-centric view of genomes …
The structural basis of the talin–KANK1 interaction that coordinates the actin and microtubule cytoskeletons at focal adhesions
X Li, BT Goult, C Ballestrem… - Open …, 2023 - royalsocietypublishing.org
Adhesion between cells and the extracellular matrix is mediated by heterodimeric (αβ)
integrin receptors that are intracellularly linked to the contractile actomyosin machinery. One …
integrin receptors that are intracellularly linked to the contractile actomyosin machinery. One …
LNCRI: Long Non-Coding RNA Identifier in Multiple Species
The pervasive nature of long non-coding RNA (lncRNA) transcription in the mammalian
genomes has changed our protein-centric view of genomes. But the identification of …
genomes has changed our protein-centric view of genomes. But the identification of …
Definition of the fibroblast adhesome using multiplexed proximity biotinylation
Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton
and transduce signals in response to both chemical and mechanical cues. The composition …
and transduce signals in response to both chemical and mechanical cues. The composition …
The purified recombinant FAT domain of the Focal Adhesion Kinase does not bind directly to recombinant Talin or MBD2 in vitro
Controlled localization and activation of the focal adhesion kinase (FAK) functionally links
adhesion, migration and survival of the cell. The C-terminal focal adhesion targeting (FAT) …
adhesion, migration and survival of the cell. The C-terminal focal adhesion targeting (FAT) …
Recognition of LD motifs by the focal adhesion targeting domains of focal adhesion kinase and proline‐rich tyrosine kinase 2‐beta: Insights from molecular dynamics …
E Michael, S Polydorides… - Proteins: Structure …, 2021 - Wiley Online Library
The focal adhesion kinase (FAK) and the proline‐rich tyrosine kinase 2‐beta (PYK2) are
implicated in cancer progression and metastasis and represent promising biomarkers and …
implicated in cancer progression and metastasis and represent promising biomarkers and …
[PDF][PDF] Molecular Insights into the Mechanism and Dynamics of Paxillin Binding to Focal Adhesions by Fluorescence Imaging Approaches
M RIPAMONTI - access.archive-ouverte.unige.ch
The organization of individual cells into functional tissues and organs is the outcome of a
multitude of cell-cell and cell-extracellular matrix (ECM) adhesive interactions (Winograd …
multitude of cell-cell and cell-extracellular matrix (ECM) adhesive interactions (Winograd …