NAPPA as a real new method for protein microarray generation

P Díez, M González-González, L Lourido, RM Dégano… - Microarrays, 2015 - mdpi.com
Nucleic Acid Programmable Protein Arrays (NAPPA) have emerged as a powerful and
innovative technology for the screening of biomarkers and the study of protein-protein …

Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions

TD Bunney, AR Cole, M Broncel, D Esposito, EW Tate… - Structure, 2014 - cell.com
Protein AMPylation, the transfer of AMP from ATP to protein targets, has been recognized as
a new mechanism of host-cell disruption by some bacterial effectors that typically contain a …

AMPylation of Rho GTPases subverts multiple host signaling processes

AR Woolery, X Yu, J LaBaer, K Orth - Journal of Biological Chemistry, 2014 - ASBMB
Rho GTPases are frequent targets of virulence factors as they are keystone signaling
molecules. Herein, we demonstrate that AMPylation of Rho GTPases by VopS is a …

Host–pathogen interaction profiling using self-assembling human protein arrays

X Yu, KB Decker, K Barker… - Journal of proteome …, 2015 - ACS Publications
Host–pathogen protein interactions are fundamental to every microbial infection, yet their
identification has remained challenging due to the lack of simple detection tools that avoid …

In silico identification of AMPylating enzymes and study of their divergent evolution

S Khater, D Mohanty - Scientific Reports, 2015 - nature.com
AMPylation is a novel post-translational modification (PTM) involving covalent attachment of
an AMP moiety to threonine/tyrosine side chains of a protein. AMPylating enzymes …

Antiviral antibody profiling by high‐density protein arrays

X Bian, P Wiktor, P Kahn, A Brunner, A Khela… - …, 2015 - Wiley Online Library
Viral infections elicit antiviral antibodies and have been associated with various chronic
diseases. Detection of these antibodies can facilitate diagnosis, treatment of infection, and …

[PDF][PDF] Biomarker Discovery for Alzheimer's Disease Using NAPPA and In Vivo Crystallization in Baculovirus-Infected Insect Cells for Structural Biology

Y Tang - 2020 - keep.lib.asu.edu
Proteins are a large collection of biomolecules that orchestrate the vital cellular processes of
life. The last decade has witnessed dramatic advances in the field of proteomics, which …

[引用][C] CURRICULUM VITAE PART I: General Information

VG Director, P Diagnostics - Cell cycle, 1993