[HTML][HTML] Cuproptosis: mechanisms and links with cancers

J Xie, Y Yang, Y Gao, J He - Molecular cancer, 2023 - Springer
Cuproptosis was a copper-dependent and unique kind of cell death that was separate from
existing other forms of cell death. The last decade has witnessed a considerable increase in …

Environmental exposure to lead (Pb) and variations in its susceptibility

J Kim, Y Lee, M Yang - … of Environmental Science and Health, Part …, 2014 - Taylor & Francis
Based on exposure frequency and intrinsic toxicity, lead (Pb) ranks one of the highest
priority toxic materials. Continuous regulation of environmental Pb exposure has contributed …

[HTML][HTML] Interpreting pathways to discover cancer driver genes with Moonlight

A Colaprico, C Olsen, MH Bailey, GJ Odom… - Nature …, 2020 - nature.com
Cancer driver gene alterations influence cancer development, occurring in oncogenes,
tumor suppressors, and dual role genes. Discovering dual role cancer genes is difficult …

MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome

K Wang, Q Liang, X Li, H Tsoi, J Zhang, H Wang… - Gut, 2016 - gut.bmj.com
Background Using the promoter methylation assay, we have shown that MDGA2 (MAM
domain containing glycosylphosphatidylinositol anchor 2) is preferentially methylated in …

[HTML][HTML] Impact of CDKN2A/B, MTAP, and TERT genetic alterations on survival in IDH wild type glioblastomas

EJ Hsu, J Thomas, EA Maher, M Youssef… - Discover Oncology, 2022 - Springer
Purpose Poor outcomes in IDH wild-type (IDHwt) glioblastomas indicate the need to
determine which genetic alterations can indicate poor survival and guidance of patient …

Cuproptosis engineered nanomaterials: The silent warrior against cancer

TS Dongsar, TT Dongsar, N Nasir, S Wahab… - Applied Materials …, 2024 - Elsevier
Regulated cell death contributes to a variety of physiological and pathological events and is
essential for maintaining physiological equilibrium. Specifically triggering programmed cell …

HNF1B inhibits cell proliferation via repression of SMAD6 expression in prostate cancer

W Lu, J Sun, H Zhou, F Wang, C Zhao… - Journal of Cellular …, 2020 - Wiley Online Library
Prostate cancer is the most common malignancy in men in developed countries. In previous
study, we identified HNF1B (Hepatocyte Nuclear Factor 1β) as a downstream effector of …

[HTML][HTML] The Role of CD4/6 Inhibitors in Breast Cancer Treatment

L Purohit, C Jones, T Gonzalez, A Castrellon… - International Journal of …, 2024 - mdpi.com
Over the last decade, treatment paradigms for breast cancer have undergone a renaissance,
particularly in hormone-receptor-positive/HER2-negative breast cancer. These revolutionary …

[HTML][HTML] Epstein-Barr virus-associated post-transplant lymphoproliferative disorders after hematopoietic stem cell transplantation: pathogenesis, risk factors and …

A Fujimoto, R Suzuki - Cancers, 2020 - mdpi.com
Epstein-Barr virus (EBV) is a ubiquitous virus belonging to the human γ-herpes virus
subfamily. After primary infection, EBV maintains a life-long latent infection. A major concern …

[HTML][HTML] Gene expression profiling of spontaneously occurring canine mammary tumours: Insight into gene networks and pathways linked to cancer pathogenesis

S Hussain, S Saxena, S Shrivastava, AK Mohanty… - PLoS …, 2018 - journals.plos.org
Spontaneously occurring canine mammary tumours (CMTs) are the most common
neoplasms of unspayed female dogs leading to thrice higher mortality rates than human …