Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines
D Ruzek, TA Županc, J Borde, A Chrdle, L Eyer… - Antiviral Research, 2019 - Elsevier
Tick-borne encephalitis (TBE) is an illness caused by tick-borne encephalitis virus (TBEV)
infection which is often limited to a febrile illness, but may lead to very aggressive …
infection which is often limited to a febrile illness, but may lead to very aggressive …
Click chemistry-aided drug discovery: A retrospective and prospective outlook
R Zhao, J Zhu, X Jiang, R Bai - European Journal of Medicinal Chemistry, 2024 - Elsevier
Click chemistry has emerged as a valuable tool for rapid compound synthesis, presenting
notable advantages and convenience in the exploration of potential drug candidates. In …
notable advantages and convenience in the exploration of potential drug candidates. In …
Recent Advances in Molecular Mechanisms of Nucleoside Antivirals
PN Kamzeeva, AV Aralov, VA Alferova… - Current Issues in …, 2023 - mdpi.com
The search for new drugs has been greatly accelerated by the emergence of new viruses
and drug-resistant strains of known pathogens. Nucleoside analogues (NAs) are a …
and drug-resistant strains of known pathogens. Nucleoside analogues (NAs) are a …
Photosensitizing antivirals
KA Mariewskaya, AP Tyurin, AA Chistov, VA Korshun… - Molecules, 2021 - mdpi.com
Antiviral action of various photosensitizers is already summarized in several comprehensive
reviews, and various mechanisms have been proposed for it. However, a critical …
reviews, and various mechanisms have been proposed for it. However, a critical …
5-(Perylen-3-ylethynyl) uracil as an antiviral scaffold: Potent suppression of enveloped virus reproduction by 3-methyl derivatives in vitro
AA Chistov, SP Chumakov, IE Mikhnovets, TD Nikitin… - Antiviral Research, 2023 - Elsevier
Amphipathic nucleoside and non-nucleoside derivatives of pentacyclic aromatic
hydrocarbon perylene are known as potent non-cytotoxic broad-spectrum antivirals. Here …
hydrocarbon perylene are known as potent non-cytotoxic broad-spectrum antivirals. Here …
Antivirals acting on viral envelopes via biophysical mechanisms of action
S Speerstra, AA Chistov, GV Proskurin, AV Aralov… - Antiviral research, 2018 - Elsevier
Most antivirals target viral proteins and are specific for only one virus, or viral type. Whereas
viral proteins are encoded in the plastic viral genome, virion lipids are not and their …
viral proteins are encoded in the plastic viral genome, virion lipids are not and their …
Examination of molecular space and feasible structures of bioactive components of humic substances by FTICR MS data mining in ChEMBL database
AA Orlov, A Zherebker, AA Eletskaya, VS Chernikov… - Scientific Reports, 2019 - nature.com
Humic substances (HS) are complex natural mixtures comprising a large variety of
compounds produced during decomposition of decaying biomass. The molecular …
compounds produced during decomposition of decaying biomass. The molecular …
Tick-borne flavivirus reproduction inhibitors based on isoxazole core linked with adamantane
DA Vasilenko, EV Dueva, LI Kozlovskaya, NA Zefirov… - Bioorganic …, 2019 - Elsevier
Infections caused by flaviviruses pose a huge threat for public health all over the world. The
search for therapeutically relevant compounds targeting tick-borne flaviviruses requires the …
search for therapeutically relevant compounds targeting tick-borne flaviviruses requires the …
Probing chemical space of tick‐borne encephalitis virus reproduction inhibitors with organoselenium compounds
AA Orlov, AA Eletskaya, KA Frolov… - Archiv der …, 2018 - Wiley Online Library
Tick‐borne encephalitis virus (TBEV), a member of the genus Flavivirus, is the leading
cause of arboviral neuroinfections in Europe. Only a few classes of the nucleoside and non …
cause of arboviral neuroinfections in Europe. Only a few classes of the nucleoside and non …
Tetrahydroquinazoline N‐oxide derivatives inhibit reproduction of tick‐borne and mosquito‐borne flaviviruses
KN Sedenkova, VI Uvarova, AA Nazarova… - Archiv der …, 2023 - Wiley Online Library
Tick‐borne encephalitis virus (TBEV), yellow fever virus (YFV), and West Nile virus (WNV)
are flaviviruses causing emerging arthropod‐borne infections of a great public health …
are flaviviruses causing emerging arthropod‐borne infections of a great public health …