Nature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural …
F Melfi, S Carradori, A Angeli… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Over the past 5 years, we have witnessed intense research activity about the
biological potential of natural products (NPs) as human monoamine oxidase B (hMAO-B) …
biological potential of natural products (NPs) as human monoamine oxidase B (hMAO-B) …
[HTML][HTML] Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors
Monoamine oxidases (MAOs), specifically MAO-A and MAO-B, play important roles in the
breakdown of monoamine neurotransmitters. Therefore, MAO inhibitors are crucial for …
breakdown of monoamine neurotransmitters. Therefore, MAO inhibitors are crucial for …
Estrogen signalling and Alzheimer's disease: Decoding molecular mechanisms for therapeutic breakthrough
In females, Alzheimer's disease (AD) incidences increases as compared to males due to
estrogen deficiency after menopause. Estrogen therapy is the mainstay therapy for …
estrogen deficiency after menopause. Estrogen therapy is the mainstay therapy for …
[HTML][HTML] New Insights on the Activity and Selectivity of MAO-B Inhibitors through In Silico Methods
L Pacureanu, A Bora, L Crisan - International Journal of Molecular …, 2023 - mdpi.com
To facilitate the identification of novel MAO-B inhibitors, we elaborated a consolidated
computational approach, including a pharmacophoric atom-based 3D quantitative structure …
computational approach, including a pharmacophoric atom-based 3D quantitative structure …
Inhibition of Monoamine Oxidases by Pyridazinobenzylpiperidine Derivatives
Monoamine oxidase inhibitors (MAOIs) have been crucial in the search for anti-
neurodegenerative medications and continued to be a vital source of molecular and …
neurodegenerative medications and continued to be a vital source of molecular and …
Nitrogen‐containing heterocyclic compounds: A ray of hope in depression?
Depression is not similar to daily mood fluctuations and temporary emotional responses to
day‐to‐day activities. Depression is not a passing problem; it is an ongoing problem. It deals …
day‐to‐day activities. Depression is not a passing problem; it is an ongoing problem. It deals …
Asymmetric Synthesis of Four Stereoisomers of 2,2-Dimethyl-3-hydroxy-4-(1′-angeloyloxy)-6-acetylchromane from Ageratina grandifolia and Plausible Absolute …
2, 2-Dimethyl-3-hydroxy-4-(1′-angeloyloxy)-6-acetylchromane is a natural product isolated
from Ageratina grandifolia that exhibits inhibitory activity against yeast α-glucosidase …
from Ageratina grandifolia that exhibits inhibitory activity against yeast α-glucosidase …
A Comprehensive Review of The Molecular Dynamic Study Of Chalcones, Coumarins and Chromones as Selective MAO‐B Inhibitors [2015‐Till Date]
R Rachel Thomas, N Chandran… - …, 2024 - Wiley Online Library
Molecular dynamics (MD) simulation is an in silico method used in the biomolecular level of
research to study how the protein interacts with the target with time. It provides a detailed …
research to study how the protein interacts with the target with time. It provides a detailed …