Evolutionary history of cotranscriptional editing in the paramyxoviral phosphoprotein gene
The phosphoprotein gene of the paramyxoviruses encodes multiple protein products. The P,
V, and W proteins are generated by transcriptional slippage. This process results in the …
V, and W proteins are generated by transcriptional slippage. This process results in the …
Molecular mechanism of de novo replication by the Ebola virus polymerase
Q Peng, B Yuan, J Cheng, M Wang, S Gao, S Bai… - Nature, 2023 - nature.com
Non-segmented negative-strand RNA viruses, including Ebola virus (EBOV), rabies virus,
human respiratory syncytial virus and pneumoviruses, can cause respiratory infections …
human respiratory syncytial virus and pneumoviruses, can cause respiratory infections …
[HTML][HTML] The nucleocapsid of paramyxoviruses: structure and function of an encapsidated template
LM Bloyet - Viruses, 2021 - mdpi.com
Viruses of the Paramyxoviridae family share a common and complex molecular machinery
for transcribing and replicating their genomes. Their non-segmented, negative-strand RNA …
for transcribing and replicating their genomes. Their non-segmented, negative-strand RNA …
[HTML][HTML] Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription
Ebola virus (EBOV) causes severe hemorrhagic fevers in humans and non-human primates.
While the role of the EBOV major matrix protein VP40 in morphogenesis is well understood …
While the role of the EBOV major matrix protein VP40 in morphogenesis is well understood …
[HTML][HTML] Phosphorylation of Ebola virus VP30 influences the composition of the viral nucleocapsid complex: impact on viral transcription and replication
N Biedenkopf, B Hartlieb, T Hoenen… - Journal of Biological …, 2013 - ASBMB
Ebola virus is a non-segmented negative-sense RNA virus causing severe hemorrhagic
fever with high fatality rates in humans and nonhuman primates. For transcription of the viral …
fever with high fatality rates in humans and nonhuman primates. For transcription of the viral …
Dynamic phosphorylation of VP30 is essential for Ebola virus life cycle
N Biedenkopf, C Lier, S Becker - Journal of virology, 2016 - Am Soc Microbiol
Ebola virus is the causative agent of a severe fever with high fatality rates in humans and
nonhuman primates. The regulation of Ebola virus transcription and replication currently is …
nonhuman primates. The regulation of Ebola virus transcription and replication currently is …
Filovirus proteins for antiviral drug discovery: Structure/function bases of the replication cycle
Filoviruses are important pathogens that cause severe and often fatal hemorrhagic fever in
humans, for which no approved vaccines and antiviral treatments are yet available. In an …
humans, for which no approved vaccines and antiviral treatments are yet available. In an …
Role of VP30 phosphorylation in the Ebola virus replication cycle
MJ Martinez, VA Volchkova, H Raoul… - The Journal of …, 2011 - academic.oup.com
Ebola virus (EBOV) transcription is dependent on the phosphoprotein VP30, a component of
the viral nucleocapsid. VP30 is phosphorylated at 2 serine residue clusters located at the N …
the viral nucleocapsid. VP30 is phosphorylated at 2 serine residue clusters located at the N …
[HTML][HTML] Evolutionary dynamics of recent peste des petits ruminants virus epidemic in China during 2013–2014
J Bao, Q Wang, L Li, C Liu, Z Zhang, J Li, S Wang… - Virology, 2017 - Elsevier
Peste des petits ruminants virus (PPRV) causes a highly contagious disease, peste des
petits ruminants (PPR), in sheep and goats which has been considered as a serious threat …
petits ruminants (PPR), in sheep and goats which has been considered as a serious threat …
Integration of global analyses of host molecular responses with clinical data to evaluate pathogenesis and advance therapies for emerging and re-emerging viral …
SD Falcinelli, DS Chertow… - ACS infectious diseases, 2016 - ACS Publications
Outbreaks associated with emerging and re-emerging viral pathogens continue to increase
in frequency and are associated with an increasing burden to global health. In light of this …
in frequency and are associated with an increasing burden to global health. In light of this …