Biosynthesis of milk fat, protein, and lactose: roles of transcriptional and posttranscriptional regulation

JS Osorio, J Lohakare, M Bionaz - Physiological genomics, 2016 - journals.physiology.org
The demand for high-quality milk is increasing worldwide. The efficiency of milk synthesis
can be improved by taking advantage of the accumulated knowledge of the transcriptional …

Functional role of PPARs in ruminants: Potential targets for fine‐tuning metabolism during growth and lactation

M Bionaz, S Chen, MJ Khan, JJ Loor - PPAR research, 2013 - Wiley Online Library
Characterization and biological roles of the peroxisome proliferator‐activated receptor
(PPAR) isotypes are well known in monogastrics, but not in ruminants. However, a wealth of …

KEGG-PATH: Kyoto encyclopedia of genes and genomes-based pathway analysis using a path analysis model

J Du, Z Yuan, Z Ma, J Song, X Xie, Y Chen - Molecular BioSystems, 2014 - pubs.rsc.org
The dynamic impact approach (DIA) represents an alternative to overrepresentation analysis
(ORA) for functional analysis of time-course experiments or those involving multiple …

[HTML][HTML] Critical review on physiological and molecular features during bovine mammary gland development: recent advances

S Jaswal, MK Jena, V Anand, A Jaswal, S Kancharla… - Cells, 2022 - mdpi.com
The mammary gland is a unique organ with the ability to undergo repeated cyclic changes
throughout the life of mammals. Among domesticated livestock species, ruminants (cattle …

PPARγ Regulates Genes Involved in Triacylglycerol Synthesis and Secretion in Mammary Gland Epithelial Cells of Dairy Goats

H Shi, J Luo, J Zhu, J Li, Y Sun, X Lin, L Zhang… - PPAR …, 2013 - Wiley Online Library
To explore the function of PPARγ in the goat mammary gland, we cloned the whole cDNA of
the PPARγ gene. Homology alignments revealed that the goat PPARγ gene is conserved …

Systems physiology in dairy cattle: nutritional genomics and beyond

JJ Loor, M Bionaz, JK Drackley - Annu. Rev. Anim. Biosci., 2013 - annualreviews.org
Microarray development changed the way biologists approach the holistic study of cells and
tissues. In dairy cattle biosciences, the application of omics technology, from spotted …

[HTML][HTML] Association of DGAT1 with cattle, buffalo, goat, and sheep milk and meat production traits

MZ Khan, Y Ma, J Ma, J Xiao, Y Liu, S Liu… - Frontiers in Veterinary …, 2021 - frontiersin.org
Milk fatty acids are essential for many dairy product productions, while intramuscular fat
(IMF) is associated with the quality of meat. The triacylglycerols (TAGs) are the major …

Heat stress negatively affects the transcriptome related to overall metabolism and milk protein synthesis in mammary tissue of midlactating dairy cows

ST Gao, L Ma, Z Zhou, ZK Zhou… - Physiological …, 2019 - journals.physiology.org
Inadequate dry matter intake only partially accounts for the decrease in milk protein
synthesis during heat stress (HS) in dairy cows. Our hypothesis is that reduced milk protein …

[HTML][HTML] Bioinformatics analysis of microRNA and putative target genes in bovine mammary tissue infected with Streptococcus uberis

A Naeem, K Zhong, SJ Moisá, JK Drackley… - Journal of dairy …, 2012 - Elsevier
MicroRNA (miRNA) are small single-stranded noncoding RNA with important roles in
regulating innate immunity in nonruminants via transcriptional and posttranscriptional …

[HTML][HTML] A decision analysis model for KEGG pathway analysis

J Du, M Li, Z Yuan, M Guo, J Song, X Xie, Y Chen - BMC bioinformatics, 2016 - Springer
Background The knowledge base-driven pathway analysis is becoming the first choice for
many investigators, in that it not only can reduce the complexity of functional analysis by …