Highlights•Thalassaemia mutation is common in some ethnic groups.•Prenatal screening
and diagnosis can prevent severe cases.•Countries receiving migrants should establish …

Abstract The Greater Middle East (GME) has been a central hub of human migration and
population admixture. The tradition of consanguinity, variably practiced in the Persian Gulf …

Purpose The aim of this review is to evaluate the prevalence of and factors associated with
keratoconus in Africa. Method A systematic online literature search was conducted for …

Despite recent biomedical breakthroughs and large genomic studies growing momentum,
the Middle Eastern population, home to over 400 million people, is underrepresented in the …

Background Marriage between close relatives has been practised globally since the early
existence of human society. The role of consanguinity and inbreeding affecting human …

Arab populations are largely understudied, notably their genetic structure and history. Here
we present an in-depth analysis of 6,218 whole genomes from Qatar, revealing extensive …

Background Pakistan has been showing consistently the highest prevalence of
consanguinity. The popularity of consanguineous marriages is not declining in the country …

The Y-chromosome has been widely used in forensic genetic applications and human
population genetic studies due to its uniparental origins. A large database on the Qatari …

The strategic location of North Africa has made the region the core of a wide range of human
demographic events, including migrations, bottlenecks, and admixture processes. This has …

Factor XI (FXI) deficiency is an autosomal bleeding disorder, usually posttrauma or
postsurgery, characterized by reduced levels of coagulation FXI in plasma. The disease is …