Application of human induced pluripotent stem cell-derived cellular and organoid models for COVID-19 research

Y Luo, M Zhang, Y Chen, Y Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its
rapid international spread has caused the coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Advanced new strategies for metastatic cancer treatment by therapeutic stem cells and oncolytic virotherapy

GT Park, KC Choi - Oncotarget, 2016 - ncbi.nlm.nih.gov
The field of therapeutic stem cell and oncolytic virotherapy for cancer treatment has rapidly
expanded over the past decade. Oncolytic viruses constitute a promising new class of …

CD40LG as a prognostic molecular marker regulates tumor microenvironment through immune process in breast cancer

M Yuan, J Pei, R Li, L Tian, X He… - International Journal of …, 2021 - Taylor & Francis
Purpose Breast cancer (BRCA) is the second most common malignancy in the world and the
most common in women. Here, we utilized publicly available BRCA dataset to investigate …

Targeted inhibition of the miR‐199a/214 cluster by CRISPR interference augments the tumor tropism of human induced pluripotent stem cell‐derived neural stem cells …

Y Luo, X Xu, X An, X Sun, S Wang… - Stem cells …, 2016 - Wiley Online Library
The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that
helps overcoming ethical and allergenic challenges posed in application of neural stem …

[HTML][HTML] Baculovirus-mediated gene delivery and RNAi applications

KE Makkonen, K Airenne, S Ylä-Herttulala - Viruses, 2015 - mdpi.com
Baculoviruses are widely encountered in nature and a great deal of data is available about
their safety and biology. Recently, these versatile, insect-specific viruses have demonstrated …

Uniparental disomy of the entire X chromosome in Turner syndrome patient-specific induced pluripotent stem cells

Y Luo, D Zhu, R Du, Y Gong, C Xie, X Xu, Y Fan, B Yu… - Cell Discovery, 2015 - nature.com
The human induced pluripotent stem cell (iPSC) technique promises to provide an unlimited,
reliable source of genetically matched pluripotent cells for personalized therapy and disease …

Competing endogenous RNA network analysis of Turner syndrome patient-specific iPSC-derived cardiomyocytes reveals dysregulation of autosomal heart …

Y Luo, Y Chen, L Ge, G Zhou, Y Chen… - Stem Cell Research & …, 2023 - Springer
Abstract Background A 45, X monosomy (Turner syndrome, TS) is the only chromosome
haploinsufficiency compatible with life. Nevertheless, the surviving TS patients still suffer …

Oncolytic adenovirus encoding decorin and CD40 ligand inhibits tumor growth and liver metastasis via immune activation in murine colorectal tumor model

Y Rong, Y Ning, J Zhu, P Feng, W Zhu, X Zhao… - Molecular …, 2024 - Springer
Colorectal cancer (CRC) is the second common cause of cancer mortality worldwide, and it
still lacks effective approaches for relapsed and metastatic CRC. Recently, oncolytic virus …

Integrative Analysis of CRISPR/Cas9 Target Sites in the Human HBB Gene

Y Luo, D Zhu, Z Zhang, Y Chen… - BioMed Research …, 2015 - Wiley Online Library
Recently, the clustered regularly interspaced short palindromic repeats (CRISPR) system
has emerged as a powerful customizable artificial nuclease to facilitate precise genetic …

High-resolution chromosomal microarray analysis of early-stage human embryonic stem cells reveals an association between X chromosome instability and skewed X …

Y Luo, J Li, D Zhu, Y Fan, S Li, X Sun - Cell & Bioscience, 2014 - Springer
X chromosome inactivation (XCI) is a dosage compensation mechanism that silences the
majority of genes on one X chromosome in each female cell via a random process. Skewed …