Application of human induced pluripotent stem cell-derived cellular and organoid models for COVID-19 research
Y Luo, M Zhang, Y Chen, Y Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its
rapid international spread has caused the coronavirus disease 2019 (COVID-19) …
rapid international spread has caused the coronavirus disease 2019 (COVID-19) …
[HTML][HTML] Advanced new strategies for metastatic cancer treatment by therapeutic stem cells and oncolytic virotherapy
The field of therapeutic stem cell and oncolytic virotherapy for cancer treatment has rapidly
expanded over the past decade. Oncolytic viruses constitute a promising new class of …
expanded over the past decade. Oncolytic viruses constitute a promising new class of …
CD40LG as a prognostic molecular marker regulates tumor microenvironment through immune process in breast cancer
M Yuan, J Pei, R Li, L Tian, X He… - International Journal of …, 2021 - Taylor & Francis
Purpose Breast cancer (BRCA) is the second most common malignancy in the world and the
most common in women. Here, we utilized publicly available BRCA dataset to investigate …
most common in women. Here, we utilized publicly available BRCA dataset to investigate …
Targeted inhibition of the miR‐199a/214 cluster by CRISPR interference augments the tumor tropism of human induced pluripotent stem cell‐derived neural stem cells …
Y Luo, X Xu, X An, X Sun, S Wang… - Stem cells …, 2016 - Wiley Online Library
The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that
helps overcoming ethical and allergenic challenges posed in application of neural stem …
helps overcoming ethical and allergenic challenges posed in application of neural stem …
[HTML][HTML] Baculovirus-mediated gene delivery and RNAi applications
KE Makkonen, K Airenne, S Ylä-Herttulala - Viruses, 2015 - mdpi.com
Baculoviruses are widely encountered in nature and a great deal of data is available about
their safety and biology. Recently, these versatile, insect-specific viruses have demonstrated …
their safety and biology. Recently, these versatile, insect-specific viruses have demonstrated …
Uniparental disomy of the entire X chromosome in Turner syndrome patient-specific induced pluripotent stem cells
Y Luo, D Zhu, R Du, Y Gong, C Xie, X Xu, Y Fan, B Yu… - Cell Discovery, 2015 - nature.com
The human induced pluripotent stem cell (iPSC) technique promises to provide an unlimited,
reliable source of genetically matched pluripotent cells for personalized therapy and disease …
reliable source of genetically matched pluripotent cells for personalized therapy and disease …
Competing endogenous RNA network analysis of Turner syndrome patient-specific iPSC-derived cardiomyocytes reveals dysregulation of autosomal heart …
Y Luo, Y Chen, L Ge, G Zhou, Y Chen… - Stem Cell Research & …, 2023 - Springer
Abstract Background A 45, X monosomy (Turner syndrome, TS) is the only chromosome
haploinsufficiency compatible with life. Nevertheless, the surviving TS patients still suffer …
haploinsufficiency compatible with life. Nevertheless, the surviving TS patients still suffer …
Oncolytic adenovirus encoding decorin and CD40 ligand inhibits tumor growth and liver metastasis via immune activation in murine colorectal tumor model
Y Rong, Y Ning, J Zhu, P Feng, W Zhu, X Zhao… - Molecular …, 2024 - Springer
Colorectal cancer (CRC) is the second common cause of cancer mortality worldwide, and it
still lacks effective approaches for relapsed and metastatic CRC. Recently, oncolytic virus …
still lacks effective approaches for relapsed and metastatic CRC. Recently, oncolytic virus …
Integrative Analysis of CRISPR/Cas9 Target Sites in the Human HBB Gene
Y Luo, D Zhu, Z Zhang, Y Chen… - BioMed Research …, 2015 - Wiley Online Library
Recently, the clustered regularly interspaced short palindromic repeats (CRISPR) system
has emerged as a powerful customizable artificial nuclease to facilitate precise genetic …
has emerged as a powerful customizable artificial nuclease to facilitate precise genetic …
High-resolution chromosomal microarray analysis of early-stage human embryonic stem cells reveals an association between X chromosome instability and skewed X …
Y Luo, J Li, D Zhu, Y Fan, S Li, X Sun - Cell & Bioscience, 2014 - Springer
X chromosome inactivation (XCI) is a dosage compensation mechanism that silences the
majority of genes on one X chromosome in each female cell via a random process. Skewed …
majority of genes on one X chromosome in each female cell via a random process. Skewed …