[HTML][HTML] Past, present, and future of deep brain stimulation: hardware, software, imaging, physiology and novel approaches
Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …
Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …
tissues. However, the specific brain structures responsible for best outcome are still debated …
Toward personalized medicine in connectomic deep brain stimulation
At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …
multitude of neurological and neuropsychiatric disorders. At the single-patient level …
[HTML][HTML] Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation
B Hollunder, JL Ostrem, IA Sahin, N Rajamani… - Nature …, 2024 - nature.com
Frontal circuits play a critical role in motor, cognitive and affective processing, and their
dysfunction may result in a variety of brain disorders. However, exactly which frontal …
dysfunction may result in a variety of brain disorders. However, exactly which frontal …
[HTML][HTML] Proceedings of the eighth annual deep brain stimulation think tank: advances in optogenetics, ethical issues affecting DBS research, neuromodulatory …
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …
Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation
The pathophysiology of dystonic tremor and essential tremor remains partially understood.
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …
[HTML][HTML] Virtual deep brain stimulation: Multiscale co-simulation of a spiking basal ganglia model and a whole-brain mean-field model with The Virtual Brain
JM Meier, D Perdikis, A Blickensdörfer… - Experimental …, 2022 - Elsevier
Deep brain stimulation (DBS) has been successfully applied in various neurodegenerative
diseases as an effective symptomatic treatment. However, its mechanisms of action within …
diseases as an effective symptomatic treatment. However, its mechanisms of action within …
[HTML][HTML] Cerebellar dysfunction as a source of dystonic phenotypes in mice
AM Brown, ME van der Heijden, HA Jinnah, RV Sillitoe - The Cerebellum, 2023 - Springer
There is now a substantial amount of compelling evidence demonstrating that the
cerebellum may be a central locus in dystonia pathogenesis. Studies using spontaneous …
cerebellum may be a central locus in dystonia pathogenesis. Studies using spontaneous …
Neuroimaging advances in deep brain stimulation: review of indications, anatomy, and brain connectomics
EH Middlebrooks, RA Domingo… - American Journal …, 2020 - Am Soc Neuroradiology
Deep brain stimulation is an established therapy for multiple brain disorders, with rapidly
expanding potential indications. Neuroimaging has advanced the field of deep brain …
expanding potential indications. Neuroimaging has advanced the field of deep brain …