Cell-derived exosomes have opened new horizons in modern therapy for advanced drug
delivery and therapeutic applications, due to their key features such as low immunogenicity …

In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

Primary ovarian insufficiency (POI) is a clinical syndrome of ovarian dysfunction
characterized by premature exhaustion of primordial follicles. POI causes infertility, severe …

Background Primary ovarian insufficiency (POI) refers to the loss of ovarian function under
the age of 40 and results in amenorrhea and infertility. Our previous studies have shown that …

Background Declining ovarian function in advance-aged women and in premature ovarian
insufficiency (POI) patients seriously affects quality of life, and there is currently no effective …

Adhesive hydrogels have been recently proposed as a potential option to seal and treat
gastric perforation (GP) which causes high mortality despite advancements in surgical …

Aims Epicardium and epicardium-derived cells are critical players in myocardial fibrosis.
Mesenchymal stem cell–derived extracellular vesicles (EVs) have been studied for cardiac …

Premature ovarian failure (POF) is a common female reproductive disorder and
characterized by menopause, increased gonadotropin levels and estrogen deficiency before …

Background Currently, there is no effective treatment for premature ovarian failure (POF),
and stem cell therapy is considered the most promising treatment. Human umbilical cord …

Background Maternal oocyte aging is strongly contributing to age-related decline in female
fertility. Coenzyme Q10 (CoQ10) exerts positive effects in improving aging-related …