The role of IgG Fc receptors in antibody-dependent enhancement
Antibody-dependent enhancement (ADE) is a mechanism by which the pathogenesis of
certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non …
certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non …
[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …
Antibody-dependent cellular phagocytosis in antiviral immune responses
MZ Tay, K Wiehe, J Pollara - Frontiers in immunology, 2019 - frontiersin.org
Antiviral activities of antibodies may either be dependent only on interactions between the
antibody and cognate antigen, as in binding and neutralization of an infectious virion, or …
antibody and cognate antigen, as in binding and neutralization of an infectious virion, or …
Immune response to dengue and Zika
A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …
are human pathogens of global significance. In particular, DENV causes the most prevalent …
Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development
The pandemic spread of a novel coronavirus–SARS coronavirus-2 (SARS-CoV-2) as a
cause of acute respiratory illness, named Covid-19, is placing the healthcare systems of …
cause of acute respiratory illness, named Covid-19, is placing the healthcare systems of …
[HTML][HTML] Antibody-dependent enhancement of coronavirus
J Wen, Y Cheng, R Ling, Y Dai, B Huang… - International Journal of …, 2020 - Elsevier
Antibody-dependent enhancement (ADE) exists in several kinds of virus. It has a negative
influence on antibody therapy for viral infection. This effect was first identified in dengue …
influence on antibody therapy for viral infection. This effect was first identified in dengue …
Functions of antibodies
DN Forthal - Microbiology spectrum, 2014 - Am Soc Microbiol
Antibodies can impact pathogens in the presence or in the absence of effector cells or
effector molecules such as complement, and experiments can often sort out with precision …
effector molecules such as complement, and experiments can often sort out with precision …
The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design
FA Rey, K Stiasny, MC Vaney, M Dellarole… - EMBO reports, 2018 - embopress.org
Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …
Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
The ongoing pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Neutralizing antibodies against SARS …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Neutralizing antibodies against SARS …