Studies and meta-analyses conflict regarding the use of early goal-directed therapy (EGDT)
for septic shock. We sought to clarify the conflict by performing a living systematic review and …

Purpose To assess the effects of early goal-directed therapy (EGDT) on reducing mortality
compared with conventional management of severe sepsis or septic shock. Materials and …

Background Sepsis and septic shock is characterized by oxidative stress that mainly
promotes systemic inflammation and organ failure due to excessive free radical production …

Background Severe sepsis can lead to organ failure and death if immediate treatment, such
as intravenous fluids and antibiotics, are not commenced within the first hour. Time-critical …

Severe sepsis and septic shock are major causes of morbidity and mortality in patients
entering the emergency department (ED) or intensive care unit (ICU). Despite substantial …

Background: Many investigators have reproduced the mortality reduction shown in the
original trial of early goal directed therapy (EGDT) in patients with severe sepsis and/or …

Цель: проанализировать клинико-экономическую целесообразность использования
селективных методов сорбции липополисахарида (ЛПС) в терапии сепсиса …

Abstract According to the CDC (2019), one in three patients who die in hospitals were
diagnosed with sepsis. Retrospective chart audits revealed high levels of nonadherence …

Increased mortality has been identified as the sepsis cascade progresses from sepsis to
severe sepsis to septic shock. Estimates reflect sepsis death rates ranging from 10% to 20 …

Nowadays, severe infection has become one of the common problems in clinic. The
morbidity of severe sepsis and septic shock is increasing, which becomes a big threat to …