Background Traumatic brain injury refers to a broad range of neurological, cognitive, and
emotional factors that result from the application of an external force to the head. Individuals …

Traumatic brain injury (TBI) is a major cause of morbidity and mortality among young
individuals worldwide. Understanding the pathophysiology of neurotrauma is crucial for the …

Dynamic brain monitoring can mitigate traumatic brain injury (TBI) deterioration and enable
precise treatment. Despite many studies on brain monitoring systems for neuroscience …

Therapeutic hypothermia was investigated repeatedly as a tool to improve the outcome of
severe traumatic brain injury (TBI), but previous clinical trials and meta-analyses found …

Cerebral blood flow (CBF) autoregulation maintains consistent blood flow across a range of
blood pressures (BPs). Sepsis is a common cause of systemic hypotension and cerebral …

Effective nursing management strategies for adults with severe traumatic brain injury (STBI)
are still a remarkable issue and a difficult task for neurologists, neurosurgeons, and …

GABAA receptor modulators are structurally almost as diverse as their target protein. A
plethora of heterocyclic scaffolds has been described as modulating this extremely important …

Background Macrophage migration inhibitory factor (MIF) is a well-known pro-inflammatory
cytokine. Serum MIF concentrations are associated with the severity and prognosis of …

Traumatic brain injury (TBI) represents a significant health crisis. To date, no FDA approved
pharmacotherapies are available to prevent the neurological deficits caused by TBI. As an …

Background S100A12 is related to acute brain injury and inflammation. We investigated the
clinical prognostic value of serum S100A12 in patients with severe traumatic brain injury …