Expert consensus on the systemic treatment of atopic dermatitis in special populations

DN Adam, MJ Gooderham, JR Beecker… - Journal of the …, 2023 - Wiley Online Library
With the increasing number of options for the treatment of moderate‐to‐severe atopic
dermatitis, clinicians need guidance on a practical approach to selecting a systemic agent …

Nomenclature and clinical phenotypes of atopic dermatitis

G Girolomoni, M de Bruin-Weller… - … advances in chronic …, 2021 - journals.sagepub.com
Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we
discuss atopic dermatitis nomenclature and identify morphologic phenotypes, which will …

Conjunctivitis in dupilumab clinical trials

B Akinlade, E Guttman‐Yassky… - British Journal of …, 2019 - academic.oup.com
Background Dupilumab blocks the shared receptor component for interleukin (IL)‐4 and IL‐
13. It is approved in the USA for patients aged≥ 12 years with moderate‐to‐severe atopic …

Efficacy and safety of multiple dupilumab dose regimens after initial successful treatment in patients with atopic dermatitis: a randomized clinical trial

M Worm, EL Simpson, D Thaçi, R Bissonnette… - JAMA …, 2020 - jamanetwork.com
Importance The dupilumab regimen of 300 mg every 2 weeks is approved for uncontrolled,
moderate to severe atopic dermatitis (AD). Objective To assess the efficacy and safety of …

Conjunctivitis in adult patients with moderate‐to‐severe atopic dermatitis: results from five tralokinumab clinical trials

A Wollenberg, LA Beck… - British Journal of …, 2022 - academic.oup.com
Background Tralokinumab, a fully human IgG4 monoclonal antibody that specifically binds
with high affinity to interleukin‐13, effectively reduces moderate‐to‐severe atopic dermatitis …

Keratoconus

RB Singh, S Koh, N Sharma, FA Woreta… - Nature Reviews …, 2024 - nature.com
Keratoconus is a progressive eye disorder primarily affecting individuals in adolescence and
early adulthood. The ectatic changes in the cornea cause thinning and cone-like steepening …

English version of clinical practice guidelines for the management of atopic dermatitis 2021

H Saeki, Y Ohya, J Furuta, H Arakawa… - The Journal of …, 2022 - Wiley Online Library
This is the English version of the Clinical Practice Guidelines for the Management of Atopic
Dermatitis 2021. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with …

[HTML][HTML] Long-term 2-year safety and efficacy of tralokinumab in adults with moderate-to-severe atopic dermatitis: interim analysis of the ECZTEND open-label …

A Blauvelt, RG Langley, JP Lacour, D Toth… - Journal of the American …, 2022 - Elsevier
Background Additional long-term treatments are needed for moderate-to-severe atopic
dermatitis (AD). An ongoing, open-label, 5-year extension trial, ECZTEND (NCT03587805) …

[HTML][HTML] A literature review of real-world effectiveness and safety of dupilumab for atopic dermatitis

M Kamata, Y Tada - JID Innovations, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin disease with pruritus, characterized by
recurrent eczema with exacerbations and remissions. AD impairs patients' QOL and places …

Risk factors for dupilumab-associated conjunctivitis in patients with atopic dermatitis

AD Treister, C Kraff-Cooper, PA Lio - JAMA dermatology, 2018 - jamanetwork.com
Importance Clinical trials of dupilumab for atopic dermatitis (AD) have reported an increased
incidence of conjunctivitis in patients who received dupilumab compared with those who …