OXA-48-like β-lactamases: global epidemiology, treatment options, and development pipeline
SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …
[HTML][HTML] Mobile genetic elements-mediated Enterobacterales-associated carbapenemase antibiotic resistance genes propagation between the environment and …
Abstract We,(1) studied carbapenem-resistant Enterobacterales (CRE) in the environment,
humans, and animals, within the same geographical area and,(2) delineated the isolates' …
humans, and animals, within the same geographical area and,(2) delineated the isolates' …
Extended‐spectrum β‐lactamase‐producing and carbapenem‐resistant Enterobacterales bloodstream infection after solid organ transplantation: Recent trends in …
E Pérez‐Nadales, M Fernández‐Ruiz… - Transplant Infectious …, 2022 - Wiley Online Library
Background Infections caused by multidrug‐resistant gram‐negative bacilli (MDR GNB), in
particular extended‐spectrum β‐lactamase‐producing (ESBL‐E) and carbapenem‐resistant …
particular extended‐spectrum β‐lactamase‐producing (ESBL‐E) and carbapenem‐resistant …
[HTML][HTML] Multidrug-resistant Klebsiella pneumoniae harboring extended spectrum β-lactamase encoding genes isolated from human septicemias
I Carvalho, NS Chenouf, JA Carvalho, AP Castro… - PLoS …, 2021 - journals.plos.org
Klebsiella pneumoniae is a major pathogen implicated in nosocomial infections. Extended-
spectrum β-lactamase (ESBL)-producing K. pneumoniae isolates are a public health …
spectrum β-lactamase (ESBL)-producing K. pneumoniae isolates are a public health …
Clinical Risk Factors and Microbiological and Intestinal Characteristics of Carbapenemase-Producing Enterobacteriaceae Colonization and Subsequent Infection
W Yuan, J Xu, L Guo, Y Chen, J Gu, H Zhang… - Microbiology …, 2022 - Am Soc Microbiol
Gastrointestinal colonization with carbapenem-resistant Enterobacteriaceae (CRE) is
always a prerequisite for the development of translocated infections. Here, we sought to …
always a prerequisite for the development of translocated infections. Here, we sought to …
Occurrence of Klebsiella pneumoniae ST244 and ST11 extensively drug-resistant producing KPC, NDM, OXA-370 in wastewater, Brazil
K Montenegro, C Flores… - Journal of Applied …, 2023 - academic.oup.com
Aims To investigate the occurrence of carbapenem-resistant Klebsiella pneumoniae (CRKP)
and their clonal relationships from hospital and municipal wastewater treatment plants …
and their clonal relationships from hospital and municipal wastewater treatment plants …
Phenotypes, genotypes and breakpoints: an assessment of β-lactam/β-lactamase inhibitor combinations against OXA-48
TE Asempa, AK Kois, CM Gill… - Journal of Antimicrobial …, 2023 - academic.oup.com
Background Two of the three recently approved β-lactam agent (BL)/β-lactamase inhibitor
(BLI) combinations have higher CLSI susceptibility breakpoints (ceftazidime/avibactam 8 …
(BLI) combinations have higher CLSI susceptibility breakpoints (ceftazidime/avibactam 8 …
[HTML][HTML] Emergence of Carbapenemase Genes in Gram-Negative Bacteria Isolated from the Wastewater Treatment Plant in A Coruña, Spain
M Nasser-Ali, P Aja-Macaya, K Conde-Pérez… - Antibiotics, 2024 - mdpi.com
Wastewater treatment plants (WWTPs) are recognized as important niches of antibiotic-
resistant bacteria that can be easily spread to the environment. In this study, we collected …
resistant bacteria that can be easily spread to the environment. In this study, we collected …
Genomic analysis of the initial dissemination of carbapenem-resistant Klebsiella pneumoniae clones in a tertiary hospital
N Garcia-Gonzalez, B Fuster, N Tormo… - Microbial …, 2023 - microbiologyresearch.org
Carbapenem-resistant Klebsiella pneumoniae is a major cause of hospital-acquired
infections and the fastest-growing pathogen in Europe. Carbapenem resistance was …
infections and the fastest-growing pathogen in Europe. Carbapenem resistance was …
Comprehensive pan-genomic, resistome and virulome analysis of clinical OXA-48 producing carbapenem-resistant Serratia marcescens strains
N Bolourchi, NN Goodarzi, CG Giske, S Nematzadeh… - Gene, 2022 - Elsevier
Abstract Background Carbapenem-resistant Enterobacteriaceae (CRE) have been
thoroughly studied as the pathogens associated with hospital acquired infections. However …
thoroughly studied as the pathogens associated with hospital acquired infections. However …