[HTML][HTML] Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Artificial intelligence aids in development of nanomedicines for cancer management

P Tan, X Chen, H Zhang, Q Wei, K Luo - Seminars in cancer biology, 2023 - Elsevier
Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …

[HTML][HTML] Immune checkpoint HLA-E: CD94-NKG2A mediates evasion of circulating tumor cells from NK cell surveillance

X Liu, J Song, H Zhang, X Liu, F Zuo, Y Zhao, Y Zhao… - Cancer Cell, 2023 - cell.com
Circulating tumor cells (CTCs), shed by primary malignancies, function as" seeds" for distant
metastasis. However, it is still largely unknown how CTCs escape immune surveillance …

[HTML][HTML] RNA sequencing: new technologies and applications in cancer research

M Hong, S Tao, L Zhang, LT Diao, X Huang… - Journal of hematology & …, 2020 - Springer
Over the past few decades, RNA sequencing has significantly progressed, becoming a
paramount approach for transcriptome profiling. The revolution from bulk RNA sequencing …

[HTML][HTML] Liquid biopsies: the future of cancer early detection

S Connal, JM Cameron, A Sala, PM Brennan… - Journal of translational …, 2023 - Springer
Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale
causing emotional, physical, and financial strains on individuals, families, and health care …

[HTML][HTML] Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

[HTML][HTML] Exosome-based liquid biopsies in cancer: opportunities and challenges

W Yu, J Hurley, D Roberts, SK Chakrabortty… - Annals of …, 2021 - Elsevier
Liquid biopsy in cancer has gained momentum in clinical research and is experiencing a
boom for a variety of applications. There are significant efforts to utilize liquid biopsies in …

Current and future perspectives of liquid biopsies in genomics-driven oncology

E Heitzer, IS Haque, CES Roberts… - Nature Reviews …, 2019 - nature.com
Precision oncology seeks to leverage molecular information about cancer to improve patient
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …

Unravelling tumour heterogeneity by single-cell profiling of circulating tumour cells

L Keller, K Pantel - Nature Reviews Cancer, 2019 - nature.com
Single-cell technologies have contributed to unravelling tumour heterogeneity, now
considered a hallmark of cancer and one of the main causes of tumour resistance to cancer …

Platelet biology and functions: new concepts and clinical perspectives

PEJ van der Meijden, JWM Heemskerk - Nature Reviews Cardiology, 2019 - nature.com
Platelets—blood cells continuously produced from megakaryocytes mainly in the bone
marrow—are implicated not only in haemostasis and arterial thrombosis, but also in other …