[HTML][HTML] Computational Analysis and Experimental Data Exploring the Role of Hesperetin in Ameliorating ADHD and SIRT1/Nrf2/Keap1/OH-1 Signaling

HI Mokhtar, NM Abd El-Fadeal, RM El-Sayed… - International Journal of …, 2024 - mdpi.com
Attention deficit hyperactivity disorder (ADHD) manifests as poor attention, hyperactivity, as
well as impulsive behaviors. Hesperetin (HSP) is a citrus flavanone with strong antioxidant …

Hesperetin protects against rotenone-induced motor disability and neurotoxicity via the regulation of SIRT1/NLRP3 signaling

H Ateyya, HM Atif, NM Abd El-Fadeal… - Toxicology …, 2024 - Taylor & Francis
Rotenone is a pesticide that causes complex I inhibition and is widely known to induce
motor disability and experimental Parkinson's disease (PD) in rodents. Evidence suggests a …

Quetiapine attenuates cadmium neurotoxicity by suppressing oxidative stress, inflammation, and pyroptosis

HS Althagafy, S Harakeh, SA Azhari, RM Farsi… - Molecular Biology …, 2024 - Springer
Abstract Background Cadmium (Cd) is a heavy metal with extremely harmful toxic effects on
the brain. Quetiapine (QTP) has unique neuroprotective effects with anti-inflammatory and …

The antioxidant efficacy of Syagrus coronata fixed oil in reverting rotenone-induced neurotoxicity in mice

LC de Amorim, IC Bezerra, AJ da Silva, P Gubert… - Pharmacological …, 2024 - Elsevier
Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by the
progressive loss of dopaminergic neurons, resulting in severe motor disabilities. Although …