Background: The specific etiopathogenesis of inflammatory bowel disease (IBD) is still
unknown. Although the conventional anti-inflammatory or immunomodulatory drugs …

Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …

Interleukin-17 family (IL-17s) comprises six structurally related members (IL-17A to IL-17F);
sequence homology is highest between IL-17A and IL-17F, displaying certain overlapping …

Innate lymphoid cells (ILC) are similar to T helper (Th) cells in expression of cytokines and
transcription factors. For example, RORγt is the lineage-specific transcription factor for both …

Introduction Gestational hypothyroxinemia (HTX) is a condition that occurs frequently at the
beginning of pregnancy, and it correlates with cognitive impairment, autism, and attentional …

Inflammatory bowel diseases (IBD), comprising ulcerative colitis (UC) and Crohn's disease
(CD), are complex chronic inflammatory intestinal conditions with a multifaceted pathology …

Background Ulcerative colitis (UC) is a common type of inflammatory bowel disease. Due to
the elusive pathogenesis, safe and effective treatment strategies are still lacking. Fraxini …

It is believed that short-chain fatty acids (SCFAs)—the bacterial metabolites produced by the
digestion of dietary fiber—potentially contribute to the prevention of colitis. However, this …

Interleukin IL-17 cytokines are central regulators of mucosal homeostasis and disease. In
mouse models of colonic tissue injury, IL-17A promotes epithelial barrier functions and …

Advancements in genome sequencing have expanded the scope of investigating mutations
in proteins across different diseases. Amino acid mutations in a protein alter its structure …