Alkenes and their derivatives are featured widely in a variety of natural products,
pharmaceuticals, and advanced materials. Significant efforts have been made toward the …

C–H activation is a 'simple-to-complex'transformation that nature has perfected over millions
of years of evolution. Transition-metal-catalysed C–H activation has emerged as an …

Owing to the market competitiveness and urgent societal need, an optimum speed of drug
discovery is an important criterion for successful implementation. Despite the rapid ascent of …

Over the last decade, high-valent cobalt catalysis has earned a place in the spotlight as a
valuable tool for C–H activation and functionalization. Since the discovery of its unique …

Abstract Palladium (II)‐catalyzed C (alkenyl)− H alkenylation enabled by a transient
directing group (TDG) strategy is described. The dual catalytic process takes advantage of …

The direct functionalization of C− H bonds is among the most fundamental chemical
transformations in organic synthesis. However, when the innate reactivity of the substrate …

The functionalization of C–H bonds in organic molecules is one of the most direct
approaches for chemical synthesis. Recent advances in catalysis have allowed native …

We highlight the reported developments of the palladium-catalyzed C–H activation and
functionalization of the inactive/unreactive prochiral C (sp3)–H bonds of aliphatic and …

The use of directing groups allows high levels of selectivity to be achieved in transition metal‐
catalyzed transformations. Efficient removal of these auxiliaries after successful …

The vicinal fluorofunctionalization of alkenes represents an expedient strategy for converting
feedstock olefins into valuable fluorinated molecules and as such has garnered significant …