The many flavours of mechanochemistry and its plausible conceptual underpinnings

RT O'Neill, R Boulatov - Nature Reviews Chemistry, 2021 - nature.com
Mechanochemistry describes diverse phenomena in which mechanical load affects
chemical reactivity. The fuzziness of this definition means that it includes processes as …

Release of molecular cargo from polymer systems by mechanochemistry

R Küng, R Göstl, BM Schmidt - Chemistry–A European Journal, 2022 - Wiley Online Library
The design and manipulation of (multi) functional materials at the nanoscale holds the
promise of fuelling tomorrow's major technological advances. In the realm of …

Azobenzene as a photoswitchable mechanophore

Y Li, B Xue, J Yang, J Jiang, J Liu, Y Zhou, J Zhang… - Nature Chemistry, 2024 - nature.com
Azobenzene has been widely explored as a photoresponsive element in materials science.
Although some studies have investigated the force-induced isomerization of azobenzene …

Harnessing the power of force: development of mechanophores for molecular release

BA Versaw, T Zeng, X Hu, MJ Robb - Journal of the American …, 2021 - ACS Publications
Polymers that release small molecules in response to mechanical force are promising
materials for a variety of applications ranging from sensing and catalysis to targeted drug …

Distal conformational locks on ferrocene mechanophores guide reaction pathways for increased mechanochemical reactivity

Y Zhang, Z Wang, TB Kouznetsova, Y Sha, E Xu… - Nature Chemistry, 2021 - nature.com
Mechanophores can be used to produce strain-dependent covalent chemical responses in
polymeric materials, including stress strengthening, stress sensing and network remodelling …

Polymer mechanochemistry-enabled pericyclic reactions

E Izak-Nau, D Campagna, C Baumann, R Göstl - Polymer Chemistry, 2020 - pubs.rsc.org
Over the past decades, it became clear that next to heat and light, pericyclic reactions can be
induced mechanochemically when the reacting motifs are embedded as latent force …

Three concomitant C–C dissociation pathways during the mechanical activation of an N-heterocyclic carbene precursor

R Nixon, G De Bo - Nature Chemistry, 2020 - nature.com
Chemical reactions usually proceed through a radical, concerted or ionic mechanism;
transformations in which all three mechanisms occur are rare. In polymer …

Force-controlled release of small molecules with a rotaxane actuator

L Chen, R Nixon, G De Bo - Nature, 2024 - nature.com
Force-controlled release of small molecules offers great promise for the delivery of drugs
and the release of healing or reporting agents in a medical or materials context,–. In polymer …

Heterolytic bond cleavage in a scissile triarylmethane mechanophore

JR Hemmer, C Rader, BD Wilts, C Weder… - Journal of the …, 2021 - ACS Publications
Covalent mechanophores display the cleavage of a weak covalent bond when a sufficiently
high mechanical force is applied. Three different covalent bond breaking mechanisms have …

Mechanochemical Release of Non‐Covalently Bound Guests from a Polymer‐Decorated Supramolecular Cage

R Küng, T Pausch, D Rasch, R Göstl… - Angewandte Chemie …, 2021 - Wiley Online Library
Supramolecular coordination cages show a wide range of useful properties including, but
not limited to, complex molecular machine‐like operations, confined space catalysis, and …